Evidence map›Paper›PMID 40703006›Full record

ReviewCancer reports (Hoboken, N.J.)2025

Diagnosis and Management of Invasive Pleomorphic Lobular Carcinoma of the Breast: A Case Report and Comprehensive Review of Current Literature.

Xiaoyu Sun, Yanze Liu, Mei Wu, Jiaqi Liu

Abstract readCase ReportsReview
In one paragraph

Review in Cancer reports (Hoboken, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xiaoyu SunAttending Physician, MM, Department of Pathology, Zibo Central Hospital, Shandong Zibo, China.ORCID 0000-0002-2103-7799
Yanze LiuResident Physician, MM, Department of Breast and Thyroid Surgery, Zibo Central Hospital, Shandong Zibo, China.ORCID 0009-0007-1266-2588
Mei WuNurse-In-Charge, BS, Zibo Central Hospital, Shandong Zibo, China.ORCID 0009-0004-6110-1224
Jiaqi LiuAttending Physician, PhD, Department of Breast and Thyroid Surgery, Zibo Central Hospital, Shandong Zibo, China.ORCID 0000-0001-5595-5988

Funding

Beijing Medical Award Foundation YXJL-2024-1352-0453
6 · The paper itself

Abstract

introductionInvasive pleomorphic lobular carcinoma (IPLC) is a rare and aggressive variant of invasive lobular breast cancer, characterized by its distinct histological features and potential for metastatic spread. This case report aims to highlight the diagnostic challenges of IPLC, particularly regarding its imaging and pathological characteristics, and to review the latest treatment protocols. CASE PRESENTATION: A 43-year-old female presented with a painless right breast mass that had persisted for 4 months. The breast ultrasound and mammography did not provide an accurate assessment, whereas MRI indicated multiple abnormal signals throughout the right breast, classified as BI-RADS 4c. Surgical intervention and subsequent pathological examination confirmed the diagnosis of multifocal invasive pleomorphic lobular carcinoma with lymph node metastasis.

conclusionIPLC presents diagnostic challenges due to its rare and aggressive nature, requiring a high degree of clinical suspicion. This case underscores the importance of comprehensive imaging and pathological assessment for the accurate diagnosis and treatment of IPLC. The standard treatment involves modified radical mastectomy, lymph node dissection, and postoperative chemotherapy.

Indexed as

Breast NeoplasmsCarcinoma, LobularAdultBreastFemaleHumansLymphatic MetastasisLymph Node ExcisionMagnetic Resonance ImagingMammographyMastectomy, Modified RadicalUltrasonography, Mammarybreast cancerchemotherapyimaging challengesinvasive pleomorphic lobular carcinomalymph node metastasismodified radical mastectomy

Identifiers

PMID40703006
PMCPMC12287662

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.