Evidence map›Paper›PMID 40702898›Full record

SynthesisJournal of cosmetic dermatology2025

Aging and Herbal Interventions: Mechanistic Insights and Therapeutic Potential.

Divyesh Suvedi, Anand Kumar, Sonika Kalia, Arun Kumar, Sapna Koul, Abija James, Deepak Kumar, Rupak Nagraik, Henok Gulilat

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of cosmetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Divyesh SuvediFaculty of Applied Sciences and Biotechnology, Shoolini University, Solan, Himachal Pradesh, India.
Anand KumarDepartment of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Shoolini University, Solan, Himachal Pradesh, India.
Sonika KaliaDepartment of Biotechnology, School of Applied and Life Sciences, Uttaranchal University, Dehradun, India.
Arun KumarPolish Academy of Sciences, Institute of Biochemistry and Biophysics, Warsaw, Poland.
Sapna KoulFaculty of Applied Sciences and Biotechnology, Shoolini University, Solan, Himachal Pradesh, India.
Abija JamesFaculty of Applied Sciences and Biotechnology, Shoolini University, Solan, Himachal Pradesh, India.
Deepak KumarDepartment of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Shoolini University, Solan, Himachal Pradesh, India.
Rupak NagraikFaculty of Applied Sciences and Biotechnology, Shoolini University, Solan, Himachal Pradesh, India.ORCID https://orcid.org/0000-0003-2783-0007
Henok GulilatDepartment of Biomedical Sciences, Institute of Health, Jimma University, Jimma, Oromia, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSkin aging is a multifactorial process influenced by an individual's genetic predisposition, lifestyle choices, and environmental factors. This process leads to epidermal thinning, a reduction in collagen and elastin levels, and a decrease in skin suppleness. While aging cannot be entirely prevented, its effects can be mitigated through the application of appropriate skincare products.

aimThis review examines the potential of natural herbal extracts in anti-aging skincare formulations, focusing on their bioactivity and safety, which aligns with current consumer trends favoring natural, organic, and eco-friendly products.

methodsA systematic literature review was performed with the help of PubMed and ScienceDirect to thoroughly examine articles between 2000 and 2025. The review made use of key phrases including "skin aging," "herbal extracts," and "anti-aging cosmetics."

resultsBioactive compounds such as polyphenols, flavonoids, and essential oils, present in plants, confer multiple benefits for the skin, including moisturizing properties, barrier repair agents, antioxidants, sunscreens, and anti-inflammatory effects. These compounds also protect and rejuvenate the skin through distinct anti-aging mechanisms.

conclusionThe use of herbal extracts in combination with nano-formulations enhances the efficacy of skincare regimens while improving stability. The integration of plant-based resources, when combined with a balanced diet and a healthy lifestyle, can significantly enhance holistic and effective anti-aging skincare.

Indexed as

PhytotherapyPlant ExtractsSkin AgingAntioxidantsCosmeticsHumansRejuvenationSkinSkin CareAntioxidantsCosmeticsPlant Extractsclinical trialsherbal extractsnano‐formulationsnatural cosmeticsskin aging

Identifiers

PMID40702898
PMCPMC12287899

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.