ArticleChemistry (Weinheim an der Bergstrasse, Germany)2025
Effective RNA Complexation by [2]Catenanes Confers Enhanced Resistance to Enzymatic Degradation.
Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Enhancing Lithium Binding Affinity, Exchange Rate, and Hard-Soft Selectivity of Catenane Ligands by Post-Interlocking Modification.Inorganic chemistry · 2026Article
- Tangled Tail of Mechanically Interlocked Peptides.Journal of the American Chemical Society · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Cationic [2]catenanes bearing l-arginine residues were synthesized via dynamic covalent self-assembly in water. These peptide-based mechanically interlocked molecules (MIMs) exhibit proteolytic stability, efficiently complex small-interfering RNA (siRNA), and protect it from nuclease degradation. Their performance in siRNA binding is attributed to multivalency and preorganization enforced by the mechanical bond.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.