Evidence map›Paper›PMID 40702775›Full record

Trial reportAnnals of medicine2025

Remifentanil enhances the sedative effect of remimazolam during anesthesia induction in patients undergoing hysteroscopy: a randomized controlled trial.

Zhengui Xie, Yeqing Liao, Qiuling Chen, Cuiwen Zhang, Jiaxin Luo, Huiyu Cao, Yuliu Lin, Hongmeng Lan, Xiaofang Huang, Xuehai Guan

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zhengui XieDepartment of Anesthesiology, the First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, PR China.
Yeqing LiaoDepartment of Anesthesiology, the First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, PR China.
Qiuling ChenDepartment of Anesthesiology, the First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, PR China.
Cuiwen ZhangDepartment of Anesthesiology, the First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, PR China.
Jiaxin LuoDepartment of Anesthesiology, the First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, PR China.
Huiyu CaoDepartment of Anesthesiology, the First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, PR China.ORCID 0000-0003-4544-8063
Yuliu LinDepartment of Anesthesiology, the First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, PR China.
Hongmeng LanDepartment of Anesthesiology, the First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, PR China.
Xiaofang HuangDepartment of Anesthesiology, the First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, PR China.
Xuehai GuanDepartment of Anesthesiology, the First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, PR China.ORCID 0000-0001-8775-6916

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRemimazolam is a novel, short-acting benzodiazepine. This study aimed to investigate whether remifentanil enhances the sedative effect of remimazolam during anesthesia induction in patients undergoing hysteroscopy.

methodsWe included 258 adult patients who underwent hysteroscopy. Patients were randomly allocated to three groups (

resultsThe time from remimazolam administration to LOC was 154 (139, 180), 120 (104, 139), and 117 (105, 135) s in the saline group, remifentanil-1group, and remifentanil-2 groups, respectively (

conclusionRemifentanil enhances the sedative effect of remimazolam during anesthesia induction in patients undergoing hysteroscopy. CLINICAL

trial registrationThe trial was registered at http://www.chictr.org.cn (ChiCTR2200062983).

Indexed as

BenzodiazepinesHypnotics and SedativesHysteroscopyPiperidinesRemifentanilAdultDouble-Blind MethodDrug SynergismFemaleHumansMiddle AgedBenzodiazepinesHypnotics and SedativesPiperidinesRemifentanilremimazolamAnesthesia inductionhysteroscopyremifentanilremimazolamsedation

Identifiers

PMID40702775
PMCPMC12291230

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.