Trial reportBMC public health2025
Cardiometabolic outcome of MyBFF@school intervention program among primary schoolchildren: a cluster randomized controlled trial.
Trial report in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04155255 (My Body is Fit and Fabulous), which is not on this map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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My Body is Fit and Fabulous: an Intervention Program to Combat Obesity Among Malaysian School Children
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11 authors.
Funding
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Abstract
backgroundThe increasing prevalence of obesity is associated with the increase in type 2 diabetes, dyslipidemia and hypertension among children. The MyBFF@school study aimed to assess the effectiveness of a 6-month intervention program on the cardiometabolic markers of the overweight and obese primary schoolchildren.
methodsMyBFF@school is a cluster randomized controlled trial involving 23 of 1196 government schools in Malaysia. Schoolchildren aged
resultsAt the end of the intervention, both the intervention and control groups had significantly increased BMI, however, when adjusted for gender and age, the BMI z-score in the intervention group showed no changes, whereas the control group had a significant increase in BMI z-score (mean difference of 0.03, 95% CI: 0.04, 0.06, p = 0.026). Fasting insulin showed significant reduction in the intervention group (-3.16 μU/mL (95% CI: -4.07, -2.25), p < 0.001) vs control (-1.05 μU/mL (95% CI: -2.28, 0.18), p = 0.095) (p < 0.001 between groups). A significantly greater reduction of HOMA-IR was observed in the intervention group [-0.41 (95% CI: - 0.63, -0.19), p < 0.001] vs control [-0.17 (95% CI: -0.45, 0.11), p = 0.231)] (p < 0.001 between groups). HDL-C also showed significant increment of 0.34 mmol/L [(95% CI: 0.32, 0.36), p < 0.001] in the intervention and 0.11 mmol/L [(95% CI: 0.08, 0.14), p < 0.001] in the control group (p < 0.001 between groups). A significant reduction of TG: HDL-C ratio was observed in both the intervention [-0.17 mmol/L (95% CI: -0.21, -0.12), p < 0.001] and control groups [-0.12 mmol/L (95% CI: -0.17, -0.07), p < 0.001] (p = 0.524 between groups).
conclusionMyBFF@school resulted in significant improvements of fasting insulin, HOMA-IR and HDL-C in the intervention group. We recommend MyBFF@school program to improve the cardiometabolic markers of the overweight and obese primary schoolchildren.
trial registrationClinical trial number: NCT04155255, November 7, 2019 (Retrospective registered). National Medical Research Register: NMRR-13-439-16563. Registered July 23, 2013. The Medical Research and Ethics Committee (MREC), Ministry of Health Malaysia and Educational Planning and Research Division (EPRD), Ministry of Education Malaysia approved the intervention program. It was funded by the Ministry of Health Malaysia.
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