ArticleHormones (Athens, Greece)2025
The association between body mass index and total lumbar bone mineral density in obese adults: the national health and nutrition examination survey (NHANES) 2011-2020.
Article in Hormones (Athens, Greece), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Beyond Weight Loss: Skeletal Considerations in Obesity Treatment.Endocrinology and metabolism (Seoul, Korea) · 2026Review
- Parathyroid disease, gut microbiome, biologic age, and more.Hormones (Athens, Greece) · 2025Article
- Parathyroid disease, gut microbiome, biologic age, and more.Hormones (Athens, Greece) · 2025Article
- Relationship between serum ApoB-100 and lumbar bone mineral density in postmenopausal women: a retrospective analysis of a health screening population.Frontiers in endocrinology · 2025Article
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Authors and funding
5 authors.
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Abstract
introductionThis study aimed to investigate the relationship between BMI and total lumbar BMD in obese adults.
methodsThe current cross-sectional study included 3,708 obese individuals. The data on BMI, total lumbar BMD, and other covariates were obtained from the National Health and Nutritional Examination Survey (NHANES) ( http://www.cdc.gov/nchs/nhanes/ ) between 2011 and March 2020 prior to the COVID-19 pandemic. Multivariate logistic regression models were utilized to investigate the association between BMI and total lumbar BMD. Smooth curve fittings and generalized additive models were used to analyze the potential non-linearity.
resultsA total of 3,708 participants (1,610 males and 2,098 females) were included in the study. In multivariate regression analysis, the association between BMI and total lumbar BMD was positive (β = 0.003, 95% CI: 0.002, 0.004). This relationship still existed after being adjusted for gender, age, and race (β = 0.003, 95% CI: 0.002, 0.004) and fully adjusted for all covariates (β = 0.003, 95% CI: 0.002, 0.004). In threshold effect analysis, the relationship between BMI and total lumbar BMD followed a U-shaped curve, with the inflection point at 36.1 kg/m
conclusionThe present study revealed a positive association between BMI and lumbar BMD in obese adults, the association notably following a U-shaped curve with an inflection point at a BMI of 36.1 kg/m².
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