Evidence map›Paper›PMID 40702393›Full record

ArticleInfectious diseases and therapy2025

Clinical Characteristics and Prognosis of AIDS Complicated with Talaromycosis marneffei Infection: a Single-Center Retrospective Study.

Zhangyan Weng, Yijie Lin, Wenliang Dai, Yijuan Zheng, Huatang Zhang, Minghui Zheng, Haoyi He, Youzhi Hong, Dawu Zeng, Zhijun Su and 1 more

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In one paragraph

Article in Infectious diseases and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Zhangyan Weng *Department of Infection Disease, Clinical Medical Research Center for Bacterial and Fungal Infectious Diseases of Fujian Province, Fujian Medical University Affiliated First Quanzhou Hospital, No. 250 East Street, Licheng District, Quanzhou, 362000, Fujian, China.
Yijie Lin *Department of Infection Disease, Clinical Medical Research Center for Bacterial and Fungal Infectious Diseases of Fujian Province, Fujian Medical University Affiliated First Quanzhou Hospital, No. 250 East Street, Licheng District, Quanzhou, 362000, Fujian, China.
Wenliang Dai *Department of Respiratory and Critical Care Medicine, Nan'an First Hospital, Quanzhou, 362000, China.
Yijuan ZhengDepartment of Infection Disease, Clinical Medical Research Center for Bacterial and Fungal Infectious Diseases of Fujian Province, Fujian Medical University Affiliated First Quanzhou Hospital, No. 250 East Street, Licheng District, Quanzhou, 362000, Fujian, China.
Huatang ZhangDepartment of Infection Disease, Clinical Medical Research Center for Bacterial and Fungal Infectious Diseases of Fujian Province, Fujian Medical University Affiliated First Quanzhou Hospital, No. 250 East Street, Licheng District, Quanzhou, 362000, Fujian, China.
Minghui ZhengDepartment of Infection Disease, Clinical Medical Research Center for Bacterial and Fungal Infectious Diseases of Fujian Province, Fujian Medical University Affiliated First Quanzhou Hospital, No. 250 East Street, Licheng District, Quanzhou, 362000, Fujian, China.
Haoyi HeDepartment of Infection Disease, Clinical Medical Research Center for Bacterial and Fungal Infectious Diseases of Fujian Province, Fujian Medical University Affiliated First Quanzhou Hospital, No. 250 East Street, Licheng District, Quanzhou, 362000, Fujian, China.
Youzhi Hong *Department of Respiratory and Critical Care Medicine, Nan'an First Hospital, Quanzhou, 362000, China. 1781721351@qq.com.
Dawu Zeng *Department of Liver Center, The First Hospital Affiliated to Fujian Medical University, Fuzhou, 350005, China. zengdw1980@fjmu.edu.cn.
Zhijun Su *Department of Infection Disease, Clinical Medical Research Center for Bacterial and Fungal Infectious Diseases of Fujian Province, Fujian Medical University Affiliated First Quanzhou Hospital, No. 250 East Street, Licheng District, Quanzhou, 362000, Fujian, China. su2366@sina.com.
Xueping Yu *Department of Infection Disease, Clinical Medical Research Center for Bacterial and Fungal Infectious Diseases of Fujian Province, Fujian Medical University Affiliated First Quanzhou Hospital, No. 250 East Street, Licheng District, Quanzhou, 362000, Fujian, China. xpyu15@fudan.edu.cn.

Funding

the Major Science and Technology Innovation Project of Fujian Province 2023Y9269the National Natural Science Foundation of China 82370604the Natural Science Foundation of Fujian Province 2023J01239
6 · The paper itself

Abstract

introductionThe objective of the study was to determine the clinical features and prognostic risk factors of acquired immunodeficiency syndrome (AIDS) combined with Talaromyces marneffei (TM) infection.

methodsWe retrospectively analyzed the clinical data of 133 hospitalized patients diagnosed with AIDS and TM co-infection. Patients were divided into an improvement group and a deterioration group on the basis of their discharge outcomes. To further investigate the severity of adverse outcomes, subgroup analysis was performed on the deterioration group. Due to the issue of complete separation in the data, Firth's logistic regression model was employed to identify independent prognostic factors. Finally, the predictive performance of the model was evaluated using the receiver operating characteristic (ROC) curve.

resultsAmong 133 patients with AIDS and TM co-infection, the main manifestations were fever (93.23%) and severe immunodeficiency with median CD4

conclusionsTimely antifungal therapy and good nutritional status are key determinants of prognosis in patients with AIDS and TM co-infection. Early diagnosis, prompt initiation of effective treatment, and active nutritional support are of great significance for improving patient survival outcomes.

Indexed as

AIDSClinical characteristicsPredictive modelPrognostic risk factorsTalaromyces marneffei

Identifiers

PMID40702393
PMCPMC12339780

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.