ArticleNature neuroscience2025
Multimodal cue integration and learning in a neural representation of head direction.
Article in Nature neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- Bio-Inspired Perception-Memory Coupling for Robust LiDAR-Inertial Odometry in Dynamic Environments.Biomimetics (Basel, Switzerland) · 2026Article
- Central complex representations of self-movement are sufficient to compute wind direction in flight.Science advances · 2026Article
- Neural dynamics for working memory and evidence integration during olfactory navigation in Drosophila.Nature communications · 2026Article
- Combining sampling and attractor dynamics in spiking models of head direction systems.PLoS computational biology · 2026Article
- Uncovering persistent biases in human path integration by separating left and right trials.Scientific reports · 2026Article
- A framework for constructing insect steering circuits.PLoS computational biology · 2026Article
- Octopamine instructs head direction plasticity.bioRxiv : the preprint server for biology · 2025Article
- Emerging Insights into the Pathogenic Mechanisms of Dravet Syndrome.Neurochemical research · 2025Review
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Navigation requires us to take account of multiple spatial cues with varying levels of informativeness and learn their spatial relationships. Here we investigate this process in the Drosophila head direction system, which functions as a ring attractor and a topographic map of head direction. Using population calcium imaging and multimodal virtual reality environments, we show that increasing cue informativeness improves encoding accuracy and produces a narrower and higher bump of activity. When cues conflict, the more informative cue exerts more weight. A familiar cue is weighted more heavily and used to guide the remapping of a less familiar cue. When a cue is less informative, it is remapped more readily in response to cue conflict. All these results can be explained by an attractor model with plastic sensory synapses. Our findings provide a mechanistic explanation for how the brain assembles spatial representations through inference and learning.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.