Evidence map›Paper›PMID 40702259›Full record

ArticleMolecular psychiatry2025

Upregulation of adenosine A

Agathe Launay, Kevin Carvalho, Athénais Genin, Thibaut Gauvrit, Paola Nobili, Victoria Gomez-Murcia, Emma Augustin, Anaëlle Burgard, Johanne Gambi, Déborah Fourmy and 12 more

Abstract read
In one paragraph

Article in Molecular psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Dual CD73/AFrontiers in pharmacology · 2026
    Article
  8. Review
  9. Senescent brain cell types in Alzheimer's disease: Pathological mechanisms and therapeutic opportunities.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Agathe LaunayUniversity of Lille, Inserm, CHU Lille, UMR-S1172 Lille Neuroscience & Cognition (LilNCog), Lille, France.
Kevin CarvalhoUniversity of Lille, Inserm, CHU Lille, UMR-S1172 Lille Neuroscience & Cognition (LilNCog), Lille, France.
Athénais GeninInstitute of Functional Genomics, University of Montpellier, CNRS, INSERM, Montpellier, France.
Thibaut GauvritUniversity of Lille, Inserm, CHU Lille, UMR-S1172 Lille Neuroscience & Cognition (LilNCog), Lille, France.
Paola NobiliInstitute of Functional Genomics, University of Montpellier, CNRS, INSERM, Montpellier, France.
Victoria Gomez-MurciaUniversity of Lille, Inserm, CHU Lille, UMR-S1172 Lille Neuroscience & Cognition (LilNCog), Lille, France.
Emma AugustinUniversité Paris-Saclay, CEA, CNRS, MIRCen, Laboratoire des Maladies Neurodégénératives, Fontenay-aux-Roses, France.
Anaëlle BurgardUniversité de Strasbourg, UMR-7364 CNRS, Laboratoire de Neurosciences Cognitives et Adaptatives (LNCA), Strasbourg, France.
Johanne GambiUniversité de Strasbourg, UMR-7364 CNRS, Laboratoire de Neurosciences Cognitives et Adaptatives (LNCA), Strasbourg, France.
Déborah FourmyUniversité Paris-Saclay, CEA, CNRS, MIRCen, Laboratoire des Maladies Neurodégénératives, Fontenay-aux-Roses, France.
Bryan ThirouxUniversity of Lille, Inserm, CHU Lille, UMR-S1172 Lille Neuroscience & Cognition (LilNCog), Lille, France.
Didier VieauUniversity of Lille, Inserm, CHU Lille, UMR-S1172 Lille Neuroscience & Cognition (LilNCog), Lille, France.
Alexis-Pierre BemelmansUniversité Paris-Saclay, CEA, CNRS, MIRCen, Laboratoire des Maladies Neurodégénératives, Fontenay-aux-Roses, France.ORCID 0000-0001-7605-5225
Stephanie Le GrasCNRS, Inserm, UMR-7104, GenomEast Platform, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Université de Strasbourg, F-67400, Illkirch, France.ORCID 0000-0001-6293-6507
Luc BuéeUniversity of Lille, Inserm, CHU Lille, UMR-S1172 Lille Neuroscience & Cognition (LilNCog), Lille, France.ORCID 0000-0002-6261-4230
Miranda E OrrDepartment of Neurology, Washington University School of Medicine, St Louis, MO, 63110, USA.
Etienne AudinatInstitute of Functional Genomics, University of Montpellier, CNRS, INSERM, Montpellier, France.ORCID 0000-0002-6389-422X
Anne-Laurence BoutillierUniversité de Strasbourg, UMR-7364 CNRS, Laboratoire de Neurosciences Cognitives et Adaptatives (LNCA), Strasbourg, France.ORCID 0000-0002-2317-9280
Gilles BonventoUniversité Paris-Saclay, CEA, CNRS, MIRCen, Laboratoire des Maladies Neurodégénératives, Fontenay-aux-Roses, France.ORCID 0000-0002-2886-4228
Karine CambonUniversité Paris-Saclay, CEA, CNRS, MIRCen, Laboratoire des Maladies Neurodégénératives, Fontenay-aux-Roses, France.
Emilie Faivre *University of Lille, Inserm, CHU Lille, UMR-S1172 Lille Neuroscience & Cognition (LilNCog), Lille, France. emilie.faivre@inserm.fr.
David Blum *University of Lille, Inserm, CHU Lille, UMR-S1172 Lille Neuroscience & Cognition (LilNCog), Lille, France. david.blum@inserm.fr.ORCID 0000-0001-5691-431X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adenosine is an ubiquitous neuromodulator that ensures cerebral homeostasis. It exerts numerous functions through the activation of G-protein-coupled adenosine receptors (ARs), in particular A

Indexed as

AstrocytesHippocampusMemory DisordersReceptor, Adenosine A2AAdenosineAlzheimer DiseaseAnimalsDisease Models, AnimalMaleMiceMice, Inbred C57BLMicrogliaNeuronal PlasticityNeuronsSpatial MemoryUp-RegulationAdenosineReceptor, Adenosine A2A

Identifiers

PMID40702259
PMCPMC12532706

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.