ArticleClinical and translational allergy2025
Early Onset Asthma, But Not Aeroallergen Sensitization, Is Associated With Lung Function Impairment in Young Adulthood-A Prospective Cohort Study.
Article in Clinical and translational allergy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
2 citing papers in PubMed.
- Particulate matter levels and children's lung function in a rural cohort near a drying saline lake.Environmental epidemiology (Philadelphia, Pa.) · 2026Article
- Early Onset Asthma, But Not Aeroallergen Sensitization, Is Associated With Lung Function Impairment in Young Adulthood-A Prospective Cohort Study.Clinical and translational allergy · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
backgroundAeroallergen sensitization is a major factor in asthma, and asthma is associated with impaired lung function. The independent association between sensitization and lung function is unclear.
objectivesTo examine factors associated with lung function in adolescence, with special interests in sensitization and asthma.
methodsAll schoolchildren in grade one and two (median age 8) in two municipalities in Northern Sweden were invited to a questionnaire survey of allergic diseases and skin prick tests to aeroallergens. This was repeated at ages 12 and, at 19 years also including spirometry and n = 1495 participated at all three occasions. Associations between risk factors and FEV
resultsAeroallergen sensitization was not associated with lung function, irrespective of age at onset, type or degree of sensitization. Early-onset asthma, both persistent (B -0.35, 95% CI -0.60 to -0.09) and in remission (B -0.43, 95% CI -0.74 to -0.12) was associated with lower FEV
conclusionsAeroallergen sensitization was not independently associated with lung function. Early onset asthma was strongly associated with lung function impairments in young adulthood and in sensitized and non-sensitized individuals alike.
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