Evidence map›Paper›PMID 40701141›Full record

ArticleNeonatology2025

Preoperative Cerebral and Renal Saturations in Neonates with Congenital Heart Defects: A Prospective Cohort Study.

Carolina Michel Macías, Emmanouil Rampakakis, Marina Mir, Matthew Mazzarello, Shiran Sara Moore, Punnanee Wutthigate, Jessica Simoneau, Daniela Villegas M, Sam D Shemie, Marie Brossard-Racine and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neonatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Perioperative Monitoring of Regional Oxygen Saturation in Congenital Heart Disease: Systematic Review of Literature up to 2023.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2026
    Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Carolina Michel MacíasDivision of Neonatology, Department of Pediatrics, Montreal Children's Hospital, McGill University Health Centre, Montreal, Québec, Canada, dra.carolinamichel@gmail.com.
Emmanouil RampakakisDepartment of Pediatrics, McGill University, Executive VicePresident, JSS Medical Research, Montreal, Québec, Canada.
Marina MirFaculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada.
Matthew MazzarelloDivision of Neonatology, Department of Pediatrics, Montreal Children's Hospital, McGill University Health Centre, Montreal, Québec, Canada.
Shiran Sara MooreDivision of Neonatology, Dana Dwek Children's Hospital, Tel Aviv Medical Center, Tel Avi, Israel.
Punnanee WutthigateDivision of Neonatology, Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Jessica SimoneauDivision of Neonatology, Department of Pediatrics, Montreal Children's Hospital, McGill University Health Centre, Montreal, Québec, Canada.
Daniela Villegas MDivision of Neonatology, Department of Pediatrics, Montreal Children's Hospital, McGill University Health Centre, Montreal, Québec, Canada.
Sam D ShemieDivision of Critical Care Medicine, Montreal Children's Hospital, McGill University Health Centre, McGill University, Montreal, Québec, Canada.
Marie Brossard-RacineSchool of Physical and Occupational Therapy, Faculty of Medicine and Health Sciences, McGill University, Montreal, Québec, Canada.
Adrian DanceaDivision of Pediatric Cardiology, Department of Pediatrics, Montreal Children's Hospital, McGill University Health Center, Montreal, Québec, Canada.
Gianluca BertolizioDivision of Critical Care Medicine, Montreal Children's Hospital, McGill University Health Centre, McGill University, Montreal, Québec, Canada.
Pia WintermarkDivision of Neonatology, Department of Pediatrics, Montreal Children's Hospital, McGill University Health Centre, Montreal, Québec, Canada.
Gabriel AltitDivision of Neonatology, Department of Pediatrics, Montreal Children's Hospital, McGill University Health Centre, Montreal, Québec, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

<p>Introduction: Congenital heart disease (CHD) is one of the most common birth defects. Cerebral (cStO

methodsSingle-center prospective cohort study (Montreal Children's Hospital, Montreal, QC, Canada) was conducted, including neonates >34 weeks with CHD without chromosomal anomalies. CStO

resultsAmong 49 included neonates, 27 (55%) exhibited retrograde flow in the postductal aorta on the last day of monitoring. Prostaglandin exposure was 100% in the retrograde group vs. 27% in the non-retrograde group. CStO

conclusionDuring the first week of life, neonates with CHD who displayed retrograde aortic flow exhibited lower cStO

Indexed as

BrainCerebrovascular CirculationHeart Defects, CongenitalKidneyOxygenOxygen SaturationEchocardiographyFemaleHumansInfant, NewbornMalePreoperative PeriodProspective StudiesSpectroscopy, Near-InfraredOxygenCongenital heart diseaseFractional tissue oxygen extractionNear-infrared spectroscopyNeonateRetrograde flow

Identifiers

PMID40701141
PMCPMC12503683

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.