Evidence map›Paper›PMID 40701095›Full record

ArticleJournal of hazardous materials2025

Airborne phthalate exposures and hypertension in the Sister Study.

Jing Xu, Dale P Sandler

Abstract read
In one paragraph

Article in Journal of hazardous materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jing XuBeijing Center for Disease Prevention and Control, Beijing 100013, China.
Dale P SandlerEpidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, USA. Electronic address: sandler@niehs.nih.gov.

Funding

Genetic and Environmental Risk Factors for Breast Cancer: The Sister StudyZ01ES044005 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI SANDLER, DALE P · 1999 to 2008
$1.3M
Intramural NIH HHS Z01 ES044005
6 · The paper itself

Abstract

backgroundHypertension affects nearly a billion people globally, but the association between airborne phthalates and hypertension remains unclear.

methodsWe conducted a cross-sectional analysis of 47,465 women from the Sister Study. Exposure to airborne bis (2-ethylhexyl) phthalate (DEHP), dibutyl phthalate (DBP), and dimethyl phthalate (DMP) was estimated using the US Environmental Protection Agency's 2005 National Air Toxics Assessment database linked to participants' addresses. Hypertension was defined as systolic blood pressure ≥ 140 mm Hg, or diastolic blood pressure ≥ 90 mm Hg, or use of antihypertensive medications. Prevalence ratios (PRs) and 95 % confidence intervals (CIs) were calculated using multivariable log-binomial regression. We further used quantile-based g-computation to assess the joint effect and conducted analyses stratified by race/ethnicity.

resultsDEHP (PR

conclusionsAirborne phthalate exposures were associated with higher hypertension prevalence, especially among women other than non-Hispanic White.

Indexed as

Air PollutantsEnvironmental ExposureHypertensionPhthalic AcidsAgedCross-Sectional StudiesDibutyl PhthalateDiethylhexyl PhthalateFemaleHumansMiddle AgedAir PollutantsDibutyl PhthalateDiethylhexyl Phthalatedimethyl phthalatephthalic acidPhthalic AcidsBlood pressureHypertensionMixturePhthalates

Identifiers

PMID40701095
PMCPMC12406956

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.