Evidence map›Paper›PMID 40700624›Full record

SynthesisClinical and experimental dental research2025

Flapless Immediate Implant Placement With and Without Bone Grafting: A Systematic Review and Meta-Analysis.

Saeed Sadat Mansouri, Farhan Musaie, Abbas Mirzaei, Samad Samadizadeh, Salar Chaychi Salmasi, Tahereh Bitaraf

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Clinical and experimental dental research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Saeed Sadat MansouriDepartment of Periodontology, Faculty of Dentistry, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.
Farhan MusaieFaculty of Dentistry, Islamic Azad University, Tehran, Iran.ORCID 0000-0003-2968-8745
Abbas MirzaeiLibrary of Faculty of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.ORCID 0000-0002-5476-7050
Samad SamadizadehOral and Maxillofacial Surgeon, Private Practice, Tehran, Iran.
Salar Chaychi SalmasiResearch Committee, REDDEN Center, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
Tahereh BitarafDental Implant Research Center, Faculty of Dentistry, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.ORCID 0000-0001-5837-2796

Funding

The authors received no specific funding for this work.
6 · The paper itself

Abstract

objectivesThis study aims to evaluate the influence of bone grafting peri-implant gap on the changes in hard and soft tissues following flapless immediate implantation. MATERIAL AND

methodsA comprehensive research process was undertaken, including electronic searches of databases such as Embase, PubMed, Web of Science, and Cochrane, as well as a manual search. This approach identified relevant clinical studies until March 2024. Randomized controlled trials (RCTs) that compared flapless immediate implant placement with and without bone grafting were selected for qualitative assessment. Meta-analyses were conducted where feasible. The protocol was registered in PROSPERO with code CRD42024499377, ensuring transparency and accountability in our research.

resultsOut of 1065 articles, 5 RCTs were included, involving 179 patients who underwent placement of 179 immediate implants (92 with bone grafting and 87 without) with follow-up periods ranging from 6 to 12 months. Analysis revealed no significant differences in horizontal bone changes within 0 to 3 mm apical to the bone crest between the two groups (weighted mean difference [WMD]: 0.147 (-0.012, 0.306), I

conclusionFlapless immediate dental implants with a bone graft may enhance alveolar bone preservation, warranting further investigation.

Indexed as

Bone TransplantationDental Implantation, EndosseousImmediate Dental Implant LoadingDental ImplantsHumansRandomized Controlled Trials as TopicDental Implantsalveolar ridge augmentationbone transplantationflaplesssocket graft

Identifiers

PMID40700624
PMCPMC12285903

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.