Evidence map›Paper›PMID 40700281›Full record

ArticleGeriatrics (Basel, Switzerland)2025

The Impact of Age on the Effectiveness of Immune Checkpoint Inhibitors Therapy in Patients with Metastatic Non-Small-Cell Lung Cancer.

Yuliia Moskalenko, Oleksandr Yazykov, Olena Vasylieva, Kateryna Smiian, Tetiana Ivakhniuk, Hanna Budko, Roman Moskalenko

Abstract read
In one paragraph

Article in Geriatrics (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yuliia MoskalenkoDepartment of Oncology and Radiology, Sumy State University, 40007 Sumy, Ukraine.ORCID 0000-0002-5398-0298
Oleksandr YazykovDepartment of Surgery, Sumy State University, 40007 Sumy, Ukraine.ORCID 0000-0003-3528-9265
Olena VasylievaDepartment of Pediatric, Sumy State University, 40007 Sumy, Ukraine.
Kateryna SmiianDepartment of Pediatric, Sumy State University, 40007 Sumy, Ukraine.
Tetiana IvakhniukDepartment of Public Health, Sumy State University, 40007 Sumy, Ukraine.
Hanna BudkoDepartment of Pathology, Sumy State University, 40007 Sumy, Ukraine.
Roman MoskalenkoDepartment of Pathology, Sumy State University, 40007 Sumy, Ukraine.ORCID 0000-0002-2342-0337

Funding

Ministry of Education and Science (Ukraine) 0123U102755
6 · The paper itself

Abstract

The global aging population has led to a growing incidence of malignancies, including metastatic non-small-cell lung cancer (mNSCLC). Immunosenescence may affect the efficacy of immune checkpoint inhibitors (ICIs). The prognostic role of age in ICI-treated mNSCLC remains uncertain.

Indexed as

ageimmune checkpoint inhibitorsnon-small-cell lung cancertoxicitytreatment duration

Identifiers

PMID40700281
PMCPMC12286007

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.