Evidence map›Paper›PMID 40700259›Full record

ArticleClocks & sleep2025

Deletion of Clock Gene

Soha A Hassan, Katrin S Wendrich, Urs Albrecht

Abstract read
In one paragraph

Article in Clocks & sleep, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Deletion of Clock GeneClocks & sleep · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Soha A HassanDepartment of Biology, University of Fribourg, 1700 Fribourg, Switzerland.ORCID 0000-0001-8566-4727
Katrin S WendrichDepartment of Biology, University of Fribourg, 1700 Fribourg, Switzerland.ORCID 0000-0002-5046-049X
Urs AlbrechtDepartment of Biology, University of Fribourg, 1700 Fribourg, Switzerland.ORCID 0000-0002-0663-8676

Funding

Swiss Government Excellence Scholarship 2023.0462Swiss National Science Foundation 310030_219880/1
6 · The paper itself

Abstract

The circadian clock is a self-sustaining oscillator with a period of approximately 24 h, enabling organisms to anticipate daily recurring events, such as sunrise and sunset. Since the circadian period is not exactly 24 h and the environmental day length varies throughout the year, the clock must be periodically reset to align an organism's physiology with the natural light/dark cycle. This synchronization, known as entrainment, is primarily regulated by nocturnal light, which can be replicated in laboratory settings using a 15 min light pulse (LP) and by assessing locomotor activity. An LP during the early part of the dark phase delays the onset of locomotor activity, resulting in a phase delay, whereas an LP in the late dark phase advances activity onset, causing a phase advance. The clock gene

Indexed as

advancedelayentrainmentlightPer2 knockoutphase shiftresetting

Identifiers

PMID40700259
PMCPMC12285990

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.