Evidence map›Paper›PMID 40700167›Full record

ReviewMedicines (Basel, Switzerland)2025

Multi-Drug Resistant Gram-Negative Sepsis in Neonates: The Special Role of Ceftazidime/Avibactam and Ceftolozane/Tazobactam.

Niki Dermitzaki, Foteini Balomenou, Anastasios Serbis, Natalia Atzemoglou, Lida Giaprou, Maria Baltogianni, Vasileios Giapros

Abstract readReview
In one paragraph

Review in Medicines (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Coexistence of blaBMC microbiology · 2026
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Niki DermitzakiNeonatal Intensive Care Unit, School of Medicine, University of Ioannina, 45500 Ioannina, Greece.
Foteini BalomenouNeonatal Intensive Care Unit, School of Medicine, University of Ioannina, 45500 Ioannina, Greece.ORCID 0000-0002-0967-8673
Anastasios SerbisPediatric Department, School of Medicine, University of Ioannina, 45500 Ioannina, Greece.ORCID 0000-0001-5422-3988
Natalia AtzemoglouNeonatal Intensive Care Unit, School of Medicine, University of Ioannina, 45500 Ioannina, Greece.
Lida GiaprouNeonatal Intensive Care Unit, School of Medicine, University of Ioannina, 45500 Ioannina, Greece.
Maria BaltogianniNeonatal Intensive Care Unit, School of Medicine, University of Ioannina, 45500 Ioannina, Greece.
Vasileios GiaprosNeonatal Intensive Care Unit, School of Medicine, University of Ioannina, 45500 Ioannina, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neonatal sepsis is a major cause of morbidity and mortality in neonates. A particular concern is the increasing prevalence of antibiotic-resistant strains among neonatal intensive care units (NICUs). Two novel beta-lactam/beta-lactamase inhibitors have recently been approved for use in neonates with multidrug-resistant infections: ceftazidime/avibactam and ceftolozane/tazobactam. These agents demonstrate efficacy against a range of multidrug-resistant gram-negative pathogens, including extended-spectrum beta-lactamases (ESBL)-producing and carbapenem-resistant

Indexed as

beta-lactams/beta-lactamase inhibitorsceftazidime/avibactamceftolozane/tazobactammultidrug-resistant gram-negative bacterianeonatal sepsis

Identifiers

PMID40700167
PMCPMC12286124

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.