Secondary Hemophagocytic Lymphocytosis in Inflammatory Bowel Disease.

Jacob Boccucci, Ramalakshmi Thulluri, Chandini Kannan, Matthew Gold, Vamsi Kota

Abstract readCase Reports

In one paragraph

Article in Hematology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jacob BoccucciDepartment of Medicine, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.

Ramalakshmi ThulluriMedical College of Georgia, Augusta University, Augusta, GA 30912, USA.

Chandini KannanDepartment of Medicine, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.

Matthew GoldDepartment of Medicine, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.

Vamsi KotaDepartment of Hematology/Oncology, Medical College of Georgia, Augusta University, Augusta, GA 30912, USA.ORCID 0000-0002-5290-9289

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Clinical Significance: Hemophagocytic lymphohistiocytosis (HLH) is a rare and life-threatening condition that can go underdiagnosed due to overlapping features with severe infections. While the use of thiopurine in inflammatory bowel disease (IBD) has been associated with HLH, the majority of these patients will have a concurrent Epstein-Barr virus (EBV) infection. Case Presentation: This report presents a case of HLH in a patient previously treated with aza-thioprine for IBD without concurrent viral infection.

Indexed as

hemophagocytic lymphocytosisinflammatory bowel diseasepancytopenia

Identifiers

PMID40700100

DOI10.3390/hematolrep17040033

PMCPMC12286110

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.