Evidence map›Paper›PMID 40700063›Full record

ReviewPediatric reports2025

Cannabinoid Hyperemesis Syndrome in Adolescents: A Narrative Review.

Camilla Pietrantoni, Gaia Margiotta, Giuseppe Marano, Marianna Mazza, Francesco Proli, Giuseppe Stella, Alessia Cherubino, Francesca Viozzi, Fabiana Rita Guida, Claudia Rendeli and 3 more

Abstract readReview
In one paragraph

Review in Pediatric reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Camilla PietrantoniUnità Operativa Semplice Dipartimentale Spina Bifida e Uropatie Congenite, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Gaia MargiottaUnità Operativa Semplice Dipartimentale Spina Bifida e Uropatie Congenite, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Giuseppe MaranoUnit of Psychiatry, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, 00168 Rome, Italy.ORCID 0000-0001-7058-4927
Marianna MazzaUnit of Psychiatry, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, 00168 Rome, Italy.ORCID 0000-0002-3007-8162
Francesco ProliUnità Operativa Semplice Dipartimentale Spina Bifida e Uropatie Congenite, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Giuseppe StellaUnità Operativa Semplice Dipartimentale Spina Bifida e Uropatie Congenite, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Alessia CherubinoUnità Operativa Semplice Dipartimentale Spina Bifida e Uropatie Congenite, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Francesca ViozziUnità Operativa Semplice Dipartimentale Spina Bifida e Uropatie Congenite, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.ORCID 0009-0002-6999-0172
Fabiana Rita GuidaUnità Operativa Semplice Dipartimentale Spina Bifida e Uropatie Congenite, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.ORCID 0009-0009-9059-6381
Claudia RendeliUnità Operativa Semplice Dipartimentale Spina Bifida e Uropatie Congenite, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Roberto PolaSection of Internal Medicine and Thromboembolic Diseases, Department of Internal Medicine, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.ORCID 0000-0001-5224-2931
Eleonora GaetaniDepartment of Translational Medicine and Surgery, Fondazione Policlinico Universitario "A. Gemelli" IRCCS Università Cattolica del Sacro Cuore, 00168 Rome, Italy.
Valentina GiorgioUnità Operativa Semplice Dipartimentale Spina Bifida e Uropatie Congenite, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Università Cattolica del Sacro Cuore, 00168 Rome, Italy.ORCID 0000-0002-7448-8710

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cannabinoid hyperemesis syndrome (CHS) is characterized by a pattern of cyclic vomiting and abdominal pain despite an absence of an organic cause, occurring in regular cannabis users. This syndrome was first described in 2004. Initially considered rare, with the increased use and legalization of cannabis, a growing incidence of diagnoses has been observed. Data on the pediatric population are still scant despite the high rate of cannabis consumption in young people. In this narrative review, we aim to synthesize the growing knowledge about CHS and its epidemiology, pathophysiology, diagnosis, and management in the pediatric population. Findings in this review highlight the diagnostic challenges in pediatric patients, the limited efficacy of standard anti-emetic therapies, and the central role of cannabis cessation in treatment. This review underscores the need for increased awareness of CHS in pediatric practice to ensure timely diagnosis and avoid unnecessary investigations and interventions.

Indexed as

adolescentscannabinoid hyperemesis syndromecyclic vomiting

Identifiers

PMID40700063
PMCPMC12286159

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.