ArticleAnnals of African medicine2026
Effect of Glycated Hemoglobin and Duration of Disease on 2-min Step Test in Type 2 Diabetes Mellitus Patients.
Article in Annals of African medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundType 2 diabetes mellitus (T2DM) impairs cardiorespiratory fitness and functional capacity. The 2-minute step test (2MST) is a simple, space-efficient method to assess aerobic capacity, especially in resource-limited settings. AIMS AND
objectivesTo assess the relationship between glycated hemoglobin (HbA1c), disease duration, and 2MST performance in T2DM patients. MATERIALS AND
methodsA cross-sectional prospective study was conducted at Vydehi Institute of Medical Sciences with 150 T2DM patients (age 30-65 years, BMI <30 kg/m²). Participants performed the 2MST, and pre- and post-exercise vitals were recorded. HbA1c was measured using HPLC. Statistical analysis included Spearman correlation and regression analysis.
resultsT2DM patients performed significantly fewer steps compared to nondiabetic controls (P = 0.001). Significant associations were found between post-test parameters (MBDS, SBP) and HbA1c. No strong correlations were observed between HbA1c and posttest oxygen saturation.
conclusionThe 2MST is a useful, practical tool to evaluate functional decline in T2DM patients. Its ease of use makes it suitable for diabetes screening and management in primary care and resource-limited environments.
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