ArticleCurrent issues in molecular biology2025
Multidimensional Transcriptomics Reveals the Key Genes and Pathways Regulating the Acidity of Apples.
Article in Current issues in molecular biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Editorial for the Special Issue "Advances in Multi-Omics for Functional Genomics Studies and Molecular Breeding".Current issues in molecular biology · 2026Article
- Development and application of KASP molecular marker for accelerated breeding of low-acid Cerasus humilis cultivars.Plant cell reports · 2026Article
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Authors and funding
4 authors.
Funding
Abstract
Low-acid apples are popular among consumers, but the mechanisms behind the complex differences in acidity among varieties that are caused by high altitude are not clear. In this study, we used the 'Golden Delicious' apple and its superior variant in the Western Sichuan Plateau of China to analyze organic acid composition, content, and the expression levels of related regulated genes during fruit development. We found that the organic acid content in the variant was significantly lower than that in the 'Golden Delicious' apple. In both apples, quinic and malic acids were the predominant organic acids, while citric and tartaric acids were present in lower amounts. In this multidimensional regulatory study, we used transcriptome sequencing, cluster analysis, and weighted gene co-expression network analysis (WGCNA) to reveal that differentially expressed genes are enriched in multiple pathways affecting fruit acidity during apple development; malate dehydrogenase (MDH) affects the malic acid content of fruits of different varieties; and H
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