Evidence map›Paper›PMID 40699698›Full record

ReviewCurrent issues in molecular biology2025

Selected Medicines That Can Cause Cardiac Arrest with Asystole.

Kamila Czarnecka, Mateusz Jędrzejec, Aleksandra Kukiełczyńska, Jacek Owczarek, Łukasz Olejnik, Paweł Szymański

Abstract readReview
In one paragraph

Review in Current issues in molecular biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Preventing First and Further Decompensation in Advanced Chronic Liver Disease.Liver international : official journal of the International Association for the Study of the Liver · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kamila CzarneckaDepartment of Pharmaceutical Chemistry, Drug Analyses and Radiopharmacy, Faculty of Pharmacy, Medical University of Lodz, Muszynskiego 1, 90-151 Lodz, Poland.
Mateusz JędrzejecDepartment of Pharmaceutical Chemistry, Drug Analyses and Radiopharmacy, Faculty of Pharmacy, Medical University of Lodz, Muszynskiego 1, 90-151 Lodz, Poland.
Aleksandra KukiełczyńskaDepartment of Pharmacology and Toxicology, Military Institute of Hygiene and Epidemiology, Kozielska 4, 01-163 Warsaw, Poland.
Jacek OwczarekDepartment of Hospital Pharmacy, Faculty of Pharmacy, Medical University of Lodz, Muszynskiego 1, 90-151 Lodz, Poland.
Łukasz OlejnikDepartment of Pharmaceutical Chemistry, Drug Analyses and Radiopharmacy, Faculty of Pharmacy, Medical University of Lodz, Muszynskiego 1, 90-151 Lodz, Poland.
Paweł SzymańskiDepartment of Pharmaceutical Chemistry, Drug Analyses and Radiopharmacy, Faculty of Pharmacy, Medical University of Lodz, Muszynskiego 1, 90-151 Lodz, Poland.ORCID 0000-0003-3438-7509

Funding

Ministry of National Defence, Poland. 357/2021/DA
6 · The paper itself

Abstract

One of the most serious consequences of cardiac arrest is asystole. It can occur in patients suffering from cardio-vascular diseases or during surgery following the use of certain drugs. The aim of this study was to identify the relationship between such use and the occurrence of cardiac arrest or asystole based on a review of literature identified in Science Direct, Web of Science and PubMed. Our findings confirm that a relationship exists between the use of certain drugs and the occurrence of asystole. Most drugs which induce asystole are used in cardiovascular disease, particularly beta-blockers, calcium L-channel blockers and potassium channel blockers. Medicine which can lead to asystole are drugs used, among others, for sedation during surgeries and intended for anesthesia; however, the relationship with asystole is not as clear as for the cardio-vascular drugs. Most patients who experience asystole during surgery after administration of the same drugs had other very serious health problems. Our findings are intended to support medical professionals in anticipating the possibility of asystole after drug administration.

Indexed as

asystolecardiac arrestmedication and asystolemedicines

Identifiers

PMID40699698
PMCPMC12109815

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.