Evidence map›Paper›PMID 40699654›Full record

ArticleCurrent issues in molecular biology2025

The Effect of Kidney Transplantation and Immunosuppressive Therapy on Adipose Tissue Content and Adipocytokine Plasma Concentration-Preliminary Study.

Daria Śleboda-Taront, Joanna Stępniewska, Barbara Dołęgowska, Emilia Marchelek, Katarzyna Dołęgowska, Małgorzata Marchelek-Myśliwiec

Abstract read
In one paragraph

Article in Current issues in molecular biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Daria Śleboda-TarontDepartment of Laboratory Diagnostics, University Clinical Hospital No. 2, Powstancow Wielkopolskich 72, 70-111 Szczecin, Poland.
Joanna StępniewskaDepartment of Nephrology, Transplantology and Internal Medicine, Pomeranian Medical University, Powstancow Wielkopolskich 72, 70-111 Szczecin, Poland.ORCID 0000-0002-0801-7582
Barbara DołęgowskaDepartment of Microbiology, Immunology and Laboratory Medicine, Pomeranian Medical University, Powstancow Wielkopolskich 72, 70-111 Szczecin, Poland.ORCID 0000-0003-3138-1013
Emilia MarchelekAmerican University of the Caribbean School of Medicine, Sizer St., Preston PR1 1JQ, UK.
Katarzyna DołęgowskaDepartment of Microbiology, Immunology and Laboratory Medicine, Pomeranian Medical University, Powstancow Wielkopolskich 72, 70-111 Szczecin, Poland.ORCID 0009-0007-3198-2026
Małgorzata Marchelek-MyśliwiecDepartment of Nephrology, Transplantology and Internal Medicine, Pomeranian Medical University, Powstancow Wielkopolskich 72, 70-111 Szczecin, Poland.ORCID 0000-0002-1920-0972

Funding

Pomeranian Medical University WL-134-01/S/12/2018
6 · The paper itself

Abstract

Kidney transplantation is the preferred treatment for chronic kidney disease, significantly improving patient survival and quality of life. After the procedure, there is a gradual tendency to normalize most of the physiological and metabolic processes, but the need for immunosuppression may lead to new disorders related to the drugs' side effects and changes in proportions of body composition. The aim of the study was to analyze the concentrations of adipocytokines such as leptin, adiponectin, visfatin, and resistin, and to assess the body composition in patients with stabilized kidney graft function treated with tacrolimus, mycophenolate mofetil, and glucocorticosteroids. A total of 47 participants were enrolled, including 25 kidney transplant recipients on uniform immunosuppressive therapy and 22 healthy controls. The concentrations of leptin, adiponectin, and IL-6 in kidney transplant recipients was significantly higher than in the control group (

Indexed as

adipocytokinesadipose tissuechronic kidney diseaseimmunosuppressive therapykidney transplantation

Identifiers

PMID40699654
PMCPMC12025913

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.