Evidence map›Paper›PMID 40699616›Full record

ArticleCurrent issues in molecular biology2025

Krüppel-like Factor 4-Deficient Cells Are Sensitive to Etoposide-Induced DNA Damage.

Maxwell H Rubinstein, Aidan Conroy, Elisabeth L Pezzuto, Hadeel Al Qoronz, Patrick Wertimer, Engda G Hagos

Abstract read
In one paragraph

Article in Current issues in molecular biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. KCTD15 Enhances Stem Cell-Like Properties and Promotes Triple-Negative Breast Cancer Progression Through KLF4/β-Catenin Signaling.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Maxwell H RubinsteinDepartment of Biology, Colgate University, Hamilton, NY 13346, USA.
Aidan ConroyDepartment of Biology, Colgate University, Hamilton, NY 13346, USA.
Elisabeth L PezzutoDepartment of Biology, Colgate University, Hamilton, NY 13346, USA.ORCID 0009-0000-1589-632X
Hadeel Al QoronzDepartment of Biology, Colgate University, Hamilton, NY 13346, USA.
Patrick WertimerDepartment of Biology, Colgate University, Hamilton, NY 13346, USA.
Engda G HagosDepartment of Biology, Colgate University, Hamilton, NY 13346, USA.ORCID 0000-0003-3461-7677

Funding

Colgate University Major Grants Picker Research Fellowship and Major Grant from Colgate University Research Council.
6 · The paper itself

Abstract

Krüppel-like factor 4 (KLF4) is a highly conserved zinc-finger transcription factor involved in cellular processes such as development, differentiation, and cell cycle regulation. Previous studies show that mouse embryonic fibroblasts (MEFs) null for

Indexed as

cell cycleDNA damageDNA damage responseDNA repairgenomic instabilityKrüppel-like factor 4

Identifiers

PMID40699616
PMCPMC12026332

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.