ArticleMethods in molecular biology (Clifton, N.J.)2025
Transcriptome-Wide Characterization of Protein:RNA Interactions with UV-Crosslinking Immunoprecipitation and Sequencing.
Article in Methods in molecular biology (Clifton, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The expansion of the cell genetic code relies on post-transcriptional regulatory mechanisms that shape the expression and translation of different mRNA transcripts into functional proteins. RNA-binding proteins (RBPs) control the splicing, editing, stability, and translation of mRNAs in a timely manner, and constitute an important layer of regulation that is often underestimated in genomic studies. Here we described individual nucleotide resolution UV-crosslinking immunoprecipitation and sequencing (iCLIP), a method that allows precise in vivo annotation of RBP-RNA interactions for identifying not only mRNA targets but also the mechanisms of action by which a given RBP controls the expression of single genes or gene-operons regulating cellular functions.
Indexed as
Identifiers
40699422What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.