Evidence map›Paper›PMID 40699232›Full record

SynthesisEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2025

Nasal surgery is pivotal, not primary, in OSA surgery - a 25-year evidence based systematic review.

Kenny P Pang, Ryan C T Cheong, Joon Wei Lim, Claudio Vicini, Scott B Pang, Jin Keat Siow, Charlotte E Pang, Brian Rotenberg

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Kenny P PangAsia Sleep Centre Consultant Otolaryngology, 290 Orchard Road, Unit 18-04,, Paragon, 238859, Singapore. drkpang@gmail.com.ORCID http://orcid.org/0000-0003-3799-1891
Ryan C T CheongRoyal National ENT Hospital Consultant, Otolaryngology, London, UK.
Joon Wei LimMinistry of Health Singapore, Singapore, Singapore.
Claudio ViciniOspedeli Privati Forli, Forli, Italy.
Scott B PangLee Kong Chian Medical School, Nanyang Technological University, Singapore, Singapore.
Jin Keat SiowOtolaryngology Head and Neck Surgery National University Singapore, Nanyang Technological University, Tan Tock Seng Hospital, Singapore, Singapore.
Charlotte E PangNanyang Girls High School, Singapore, Singapore.
Brian RotenbergWestern University Otolaryngology, London, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the contribution of nasal surgery to multilevel OSA surgical success outcome.

methodsSystematic review of MEDLINE, Google Scholar, Cochrane Library and Evidence Based Medicine Reviews to identify publications relevant to OSA, nasal resistance, pharyngeal volume/space, nasal surgery, multilevel surgery and its outcomes. All relevant studies published between January 2000 to December 2024 were included.

resultsTwelve studies were included in this systematic review with 11 articles illustrating that nasal surgery was pivotal, and improved outcomes in multilevel OSA surgery, whilst nasal surgery alone for OSA did not significantly affect polysomnographic results. Five articles utilizing CBCT, 3D measurements of nasal and pharyngeal airway area/volume, computational fluid dynamics and nasal resistance demonstrated that reducing nasal resistance with nasal surgery increased the pharyngeal airway space and volume; whilst 6 articles established through clinical case studies that multilevel OSA surgery combined with nasal surgery yielded better AHI, LSAT and ESS outcomes than multilevel surgery without nasal surgery. The landmark article that reviewed 24 years of nasal surgery alone for OSA treatment, showed poor outcomes and minimal AHI change with nasal surgery alone.

conclusionAs the upper airway is a continuous air conduit, reducing nasal resistance would reduce pharyngeal pressures leading to improvement of outcome parameters. Hence, including nose surgery in multilevel surgery improves surgical success. LEVEL OF EVIDENCE: 3:

Indexed as

Nasal Surgical ProceduresSleep Apnea, ObstructiveHumansPolysomnographyTreatment OutcomeMultilevel surgeryNose surgerySuccess rate and obstructive sleep apnea

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.