ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2025
Epidemiological evolution of acute mastoiditis in children after COVID-19 pandemic.
Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeAcute mastoiditis (AM), the most common complication of acute otitis media in children, can lead to severe complications, including intracranial involvement. Since COVID-19, AM epidemiology shifted, with increased cases, altered seasonality, and new bacteria involved. This study aimed to evaluate the incidence of acute and complicated mastoiditis pre- and post-COVID, assess changes in clinical outcomes and bacterial profiles, and identify risk factors for complications.
methodsThis retrospective cohort study in a tertiary pediatric center included children under 18 diagnosed with AM confirmed by CT between March 16, 2018, and March 15, 2024. Cases were categorized into pre- and post-COVID periods. Data collected included clinical and demographic variables, treatments, and outcomes. AM was classified as'simple' or'complicated' based on clinical and radiological criteria.
resultsAmong 136 AM cases, 26.5% were complicated. Post-COVID incidence significantly increased from 31 to 105 cases, while complication rates remained stable (32.3% pre- vs. 24.8% post-COVID). Streptococcus pyogenes prevalence rose (9.7% to 34.6%), while Streptococcus pneumoniae decreased (32.3% to 11.5%). Older age, elevated CRP, and prehospital antibiotic use were significantly associated with complications. Most cases occurred in winter, while complicated cases peaked in spring. Mastoidectomy was performed in 80.6% of complicated cases, with prolonged hospital stays and extended antibiotic therapy.
conclusionAM incidence increased post-COVID, with Streptococcus pyogenes becoming the dominant pathogen. Complication rates remained stable, with older age, elevated CRP, and prehospital antibiotics as key risk factors. Continued epidemiological monitoring and management adaptation are crucial.
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