Evidence map›Paper›PMID 40699221›Full record

ArticlePlanta2025

Chitinase-activity-independent anti-insect effect of class V chitinase from fig trees (Ficus carica).

Sakihito Kitajima, Toshiharu Akino, Hideki Yoshida, Kenji Miura, Toki Taira, Kazufumi Yazaki, Ryosuke Munakata, Yutori Murata, Miku Sugimori, Naoki Tani and 1 more

Abstract read
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In one paragraph

Article in Planta, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sakihito KitajimaDepartment of Applied Biology, Kyoto Institute of Technology, Matsugasaki, Sakyo-Ku, Kyoto, 606-8585, Japan. sakito@kit.ac.jp.ORCID http://orcid.org/0000-0002-9840-6708
Toshiharu AkinoDepartment of Applied Biology, Kyoto Institute of Technology, Matsugasaki, Sakyo-Ku, Kyoto, 606-8585, Japan.
Hideki YoshidaDepartment of Applied Biology, Kyoto Institute of Technology, Matsugasaki, Sakyo-Ku, Kyoto, 606-8585, Japan.
Kenji MiuraFaculty of Life and Environmental Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, 305-8572, Japan.
Toki TairaDepartment of Bioscience and Biotechnology, University of the Ryukyus, Senbaru, Nishihara-Cho, Okinawa, 903-0213, Japan.
Kazufumi YazakiResearch Institute for Sustainable Humanosphere, Kyoto University, Uji, 611-0011, Japan.
Ryosuke MunakataResearch Institute for Sustainable Humanosphere, Kyoto University, Uji, 611-0011, Japan.
Yutori MurataDepartment of Applied Biology, Kyoto Institute of Technology, Matsugasaki, Sakyo-Ku, Kyoto, 606-8585, Japan.
Miku SugimoriDepartment of Applied Biology, Kyoto Institute of Technology, Matsugasaki, Sakyo-Ku, Kyoto, 606-8585, Japan.
Naoki TaniDepartment of Applied Biology, Kyoto Institute of Technology, Matsugasaki, Sakyo-Ku, Kyoto, 606-8585, Japan.
Eric Hyrmeya SavadogoDepartment of Applied Biology, Kyoto Institute of Technology, Matsugasaki, Sakyo-Ku, Kyoto, 606-8585, Japan.

Funding

Cooperative Research Grant of the Plant Transgenic Design Initiative (PTraD) by the Gene Research Center, Tsukuba-Plant Innovation Research Center, University of Tsukuba 2002Grant-in-Aid for Scientific Research from the Ministry of Education, Science, Sports, Culture and Technology of Japan 20K05768
6 · The paper itself

Abstract

MAIN

conclusionThe feeding assay revealed growth-retardation effects of class V chitinase of Ficus carica on Spodoptera litura larvae and these effects were retained in its chitinase-inactive mutants. This study investigated the anti-insect activity of the class V chitinase (FcChiC) from latex of the fig tree (Ficus carica, Moraceae). The feeding of radish cotyledons, transiently producing FcChiC, to larvae of Spodoptera litura (Lepidoptera), resulted in significant growth reduction. A close homolog from Cannabis sativa (Cannabaceae) also demonstrated similar effects, while six other class V chitinases from plants, including Arabidopsis thaliana ChiC, did not. Notably, the anti-insect activity of FcChiC persisted in its chitinase-inactive mutants, which maintained chitin-binding ability. These results suggested that FcChiC and its C. sativa homolog are promising candidates for further research in pest control strategies.

Indexed as

ChitinasesFicusInsecticidesSpodopteraAnimalsLarvaPlant ProteinsChitinasesInsecticidesPlant ProteinsAntipestBiotic stressCannabis sativaEntomotoxic proteinLatexLaticifer

Identifiers

PMID40699221

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.