Evidence map›Paper›PMID 40699171›Full record

Trial reportThe Journal of adolescent health : official publication of the Society for Adolescent Medicine2026

Pilot Study of a Digital Health Intervention to Increase HIV and Sexually Transmitted Infection Testing Uptake and Reduce Condomless Sex and Substance Use Among Adolescents.

David Cordova, Jose A Bauermeister, Sydni Warner, Zhuoxun Jiang, Frania Mendoza Lua, Sarah Khreizat, Jennifer MacLeod, Patricia Wells, Torsten B Neilands, Lauretta Ovadje and 4 more

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

David CordovaSchool of Social Work, University of Michigan, Ann Arbor, Michigan. Electronic address: cordovad@umich.edu.
Jose A BauermeisterSchool of Nursing, University of Pennsylvania, Philadelphia, Pennsylvania.
Sydni WarnerSchool of Public Health, University of Michigan, Ann Arbor, Michigan.
Zhuoxun JiangDepartment of Statistics, University of Michigan, Ann Arbor, Michigan.
Frania Mendoza LuaDepartment of Population Health Sciences, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
Sarah KhreizatSchool of Social Work, University of Michigan, Ann Arbor, Michigan.
Jennifer MacLeodLivingston Physician Organization, Howell, Michigan.
Patricia WellsThe Corner Health Center, Ypsilanti, Michigan.
Torsten B NeilandsDivision of Prevention Science, Department of Medicine, University of California, San Francisco, California.
Lauretta OvadjeSchool of Public Health, University of Michigan, Ann Arbor, Michigan.
Jorge DelvaSchool of Social Work, Boston University, Boston, Massachusetts.
Kathryn B FesslerThe Corner Health Center, Ypsilanti, Michigan.
Versell A SmithThe Corner Health Center, Ypsilanti, Michigan.
Cherrie B BoyerDivision of Adolescent and Young Adult Medicine, Department of Pediatrics, University of California, San Francisco, California.

Funding

Health Disparities Research Scholars Training Program-RenewalT32HD049302 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI Maureen S Durkin · 2007 to 2026
$5.6M
Preventing HIV/STI in Urban Adolescents via an mHealth Primary Care InterventionR03DA041891 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CORDOVA, DAVID · 2017 to 2018
$311k
NICHD NIH HHS T32 HD049302NIDA NIH HHS R03 DA041891
6 · The paper itself

Abstract

purposeEnhancing HIV/sexually transmitted infection testing and reducing unsafe sexual behaviors and substance use are crucial for public health, particularly among youth. This pilot study examines the Storytelling 4 Empowerment (S4E) intervention's preliminary efficacy in these areas.

methodsUsing a community-engaged research approach, we conducted a randomized controlled trial with 100 adolescents and young adults (mean age = 19.27, standard deviation = 1.62) at a youth-focused clinic in Southeast Michigan. Participants were randomized to S4E, a brief digital health intervention, or usual care. Assessments occurred at baseline, postintervention, 3 and 6 months, with statistical analyses estimating effect sizes.

resultsS4E participants demonstrated higher HIV (52% vs. 12%; h = 0.95) and sexually transmitted infection (52% vs. 20.4%; h = 0.74) testing at 6-month follow-up. Reductions in condomless sex (12.9% vs. 1%; h = 0.35) and binge drinking (11.2% vs. 1.6%; h = 0.02) were reported at 3 months. Both youth and providers in the S4E group reported better clinician-youth communication than controls, and youth showed increased improvement over time (Cohen's d = 1.19 at 6 months). DISCUSSION: The S4E intervention demonstrated significant improvements in testing, risk behaviors, and communication. These findings suggest the need for larger-scaled randomized controlled trials to confirm the intervention's efficacy for youth in clinical settings.

Indexed as

HIV InfectionsSexually Transmitted DiseasesSubstance-Related DisordersUnsafe SexAdolescentDigital HealthFemaleHumansMaleMichiganPilot ProjectsSexual BehaviorYoung AdultDigital healthHIVPrimary careSexual healthSubstance useYouth

Identifiers

PMID40699171
PMCPMC12366748

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.