ReviewCurrent opinion in infectious diseases2025
Schistosomiasis: a neglected cause of infertility in females and males.
Review in Current opinion in infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Genital schistosomiasis in non-endemic settings: a clinical perspective.Parasitology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
purpose of reviewSchistosomiasis affects over 250 million individuals worldwide and has been associated with infertility, which can harm the mental, physical, and social well being of individuals. This review aims to summarize the multiple ways in which schistosome infection can affect fertility in females and males, through functional, hormonal, and systemic processes. RECENT
findingsSchistosome infection causes functional genital tract damage through granuloma formation and fibrosis, which can lead to organ damage and obstruction in the male and female genital tracts. Hormone imbalances caused by the release of estrogen-like metabolites by schistosome worms can dysregulate the hypothalamic-pituitary-gonadal axis and disturb the menstrual cycle, ovulation, and male reproductive function. Systemic and local tissue immunologic changes in response to schistosomes may lower sperm and semen quality, hinder implantation in the uterus, or contribute to early spontaneous abortions. SUMMARY: Via an array of mechanisms, schistosome infections can impair both female and male fertility. Studies in this neglected area are limited, and further investigation into disease processes and potential therapies for both females and males are greatly needed.
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Registered trials
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