Evidence map›Paper›PMID 40699008›Full record

ArticleSleep2025

The role of confidence, motivation, and social support in positive airway pressure usage in obstructive sleep apnea: a real-world data analysis.

Leanne Kaye, Vy Vuong, Meredith A Barrett, Adam V Benjafield, Peter A Cistulli, Atul Malhotra, Jean-Louis Pépin, medXcloud group

Abstract read
In one paragraph

Article in Sleep, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Leanne KayeResmed Science Center, Medical Affairs, San Diego, CA, United States.ORCID 0000-0002-5345-7026
Vy VuongResmed Science Center, Medical Affairs, San Diego, CA, United States.
Meredith A BarrettResmed Science Center, Medical Affairs, San Diego, CA, United States.
Adam V BenjafieldResmed Science Center, Medical Affairs, San Diego, CA, United States.
Peter A CistulliCharles Perkins Centre, University of Sydney and Royal North Shore Hospital, Sydney, Australia.ORCID 0000-0002-7920-4924
Atul MalhotraUniversity of California San Diego, La Jolla, CA, United States.
Jean-Louis PépinUniversity of Grenoble Alpes, HP2 Laboratory, Inserm U1300, Grenoble, France.ORCID 0000-0003-3832-2358
medXcloud group

Funding

Is Obstructive Sleep Apnea Important in the Development of Alzheimer's DiseaseR01AG063925 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MALHOTRA, ATUL · 2020 to 2024
$3.7M
Underlying mechanisms of obesity-induced obstructive sleep apneaR01HL148436 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Atul Malhotra · 2020 to 2026
$3.4M
Sleep Apnea Endophenotypes: One Size Does Not Fit AllR01HL154926 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MALHOTRA, ATUL · 2021 to 2025
$3.3M
The cardiovascular consequences of sleep apnea plus COPD (Overlap syndrome)R01HL166485 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Atul Malhotra · 2023 to 2026
$3.1M
VentNet: A Real-Time Multimodal Data Integration Model for Prediction of Respiratory Failure in Patients with COVID-19R01HL157985 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MALHOTRA, ATUL, NEMATI, SHAMIM · 2022 to 2025
$2.9M
Developing a Diverse Next Generation of Leaders in Respiratory ScienceT32HL166127 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Laura Elise Crotty Alexander, Atul Malhotra · 2023 to 2026
$1.6M
French National Research AgencyGrenoble Alpes University Foundation ANR-23-IACL-0006NHLBI NIH HHS R01 HL148436NHLBI NIH HHS R01 HL154926NHLBI NIH HHS R01 HL157985NHLBI NIH HHS R01 HL166485NHLBI NIH HHS T32 HL166127NIA NIH HHS R01 AG063925NIH HHS
6 · The paper itself

Abstract

STUDY

objectivesDespite the well-established benefits of positive airway pressure therapy in obstructive sleep apnea, adoption and persistence rates vary widely. Self-efficacy, motivation, and social support may be important behavioral determinants of positive airway pressure usage, but few studies have examined the role of these factors in real-world populations.

methodsThis retrospective analysis examined the association between behavioral survey data and objectively measured positive airway pressure usage data among positive airway pressure therapy users with obstructive sleep apnea. A feature selection process helped to identify key behavioral predictors of positive airway pressure usage, and Firth's logistic regression estimated the association between selected behavioral determinants and short- (90 days) and long-term (360 days) positive airway pressure therapy usage. Regressions controlled for demographic and clinical factors, positive airway pressure device type, and length of therapy use.

resultsA total of 11 228 respondents were included in the 90-day assessment and 3605 were included in the 360-day assessment. Confidence to stay on therapy, identification of a motivator, and involvement of a health care provider were significantly associated with greater odds of both short- and long-term positive airway pressure usage. In males and females, confidence was a significant determinant of greater odds of positive airway pressure usage, but there were gender differences by the type of motivation and the importance of social support.

conclusionsConfidence, motivation, and healthcare provider involvement may play an important role in achieving both short- and long-term positive airway pressure therapy usage. These insights, alongside the observed differences in behavioral drivers by gender, suggest an opportunity to better understand and tailor positive airway pressure follow-up strategies that leverage behavior change determinants. Statement of Significance Despite the well-established benefit of positive airway pressure (PAP) therapy for the treatment of obstructive sleep apnea (OSA), patient usage can vary widely. This study is one of the largest real-world investigations of behavioral factors associated with PAP usage, including patient self-efficacy, motivation, and social support. Our findings underscore the importance of confidence, motivational factors, and healthcare provider involvement in achieving short- and long-term PAP therapy usage. Notably, we also identified key gender differences, reinforcing the importance of personalized approaches. Our study provides actionable strategies for PAP adherence interventions, with implications for improving long-term OSA management.

Indexed as

Continuous Positive Airway PressureMotivationPatient ComplianceSelf EfficacySleep Apnea, ObstructiveSocial SupportAdultAgedFemaleHumansMaleMiddle AgedRetrospective StudiesSurveys and Questionnairesbehavioral determinantsconfidencegender differencesmotivationobstructive sleep apneapositive airway pressureself-efficacysocial support

Identifiers

PMID40699008
PMCPMC12679665

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.