Evidence map›Paper›PMID 40698983›Full record

ArticlemBio2025

Revisiting oxygen toxicity: evolution and adaptation to superoxide in a SOD-deficient bacterial pathogen.

Samuel G Huete, Alejandro Leyva, Etienne Kornobis, Thomas Cokelaer, Pierre Lechat, Marc Monot, Rosario Duran, Mathieu Picardeau, Nadia Benaroudj

Abstract read
In one paragraph

Article in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. The Single-Step Method of RNA Purification Applied to Leptospira.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Samuel G HueteBiology of Spirochetes, Institut Pasteur, CNRS UMR 6047, Université Paris Cité, Paris, France.ORCID 0000-0002-3029-0753
Alejandro LeyvaAnalytical Biochemistry and Proteomics Unit, Instituto de Investigaciones Biológicas Clemente Estable, Institut Pasteur de Montevideo, Montevideo, Uruguay.
Etienne KornobisPlate-forme Technologique Biomics, Institut Pasteur, Université Paris Cité, Paris, France.
Thomas CokelaerPlate-forme Technologique Biomics, Institut Pasteur, Université Paris Cité, Paris, France.
Pierre LechatBioinformatics of Biostatistics Hub, Institut Pasteur, Université Paris Cité, Paris, France.
Marc MonotPlate-forme Technologique Biomics, Institut Pasteur, Université Paris Cité, Paris, France.
Rosario DuranAnalytical Biochemistry and Proteomics Unit, Instituto de Investigaciones Biológicas Clemente Estable, Institut Pasteur de Montevideo, Montevideo, Uruguay.ORCID 0000-0002-8575-9651
Mathieu PicardeauBiology of Spirochetes, Institut Pasteur, CNRS UMR 6047, Université Paris Cité, Paris, France.ORCID 0000-0002-5338-5579
Nadia BenaroudjBiology of Spirochetes, Institut Pasteur, CNRS UMR 6047, Université Paris Cité, Paris, France.ORCID 0000-0002-6475-0041

Funding

Virulence and Adaptation to the Host Environment of Pathogenic LeptospiraP01AI168148 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DAVID A HAAKE · 2023 to 2026
$11.8M
FOCEM-COF FOCEM-COF 03/11Institut Pasteur PTR2019-310NIAID NIH HHS P01 AI168148NIH HHS P01 AI 168148
6 · The paper itself

Abstract

Dioxygen (O

Indexed as

Adaptation, PhysiologicalLeptospiraOxygenSuperoxide DismutaseSuperoxidesBacterial ProteinsEvolution, MolecularBacterial ProteinsOxygenSuperoxide DismutaseSuperoxidesevolutionLeptospiraoxygen toxicityregulation of gene expressionRNA-seqspirochetessulfur assimilatory pathwaysuperoxide dismutase

Identifiers

PMID40698983
PMCPMC12345160

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.