Evidence map›Paper›PMID 40698895›Full record

ArticleActa orthopaedica2025

Association of tourniquet use on short-term implant survival after primary total knee arthroplasty: a study of 24,249 knees from the Norwegian Arthroplasty Register.

Michelle Khan, Stein Håkon Låstad Lygre, Mona Badawy, Otto Schnell Husby, Geir Hallan, Paul Johan Høl, Jan-Erik Gjertsen, Ove Furnes

Abstract read
In one paragraph

Article in Acta orthopaedica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Michelle KhanDepartment of Clinical Medicine, University of Bergen, Bergen, Norway. michi.khan.mk@gmail.com.
Stein Håkon Låstad LygreThe Norwegian Arthroplasty Register, Department of Orthopaedic Surgery, Haukeland University Hospital, Bergen; Department of Occupational Medicine, Haukeland University Hospital, Bergen, Norway.
Mona BadawyThe Coastal Hospital at Hagevik, Hagevik, Norway.ORCID 0000-0001-6529-1484
Otto Schnell HusbyDepartment of Neuromedicine and Movement Science, Faculty of Medicine and Health Science, Norwegian University of Science and Technology, Trondheim; Department of Orthopaedic Surgery, Health Møre and Romsdal HF, Kristiansund Hospital, Kristiansund, Norway.
Geir HallanDepartment of Clinical Medicine, University of Bergen, Bergen; The Norwegian Arthroplasty Register, Department of Orthopaedic Surgery, Haukeland University Hospital, Bergen; The Coastal Hospital at Hagevik, Hagevik, Norway.
Paul Johan HølDepartment of Clinical Medicine, University of Bergen, Bergen; Department of Orthopaedic Surgery, Biomatlab, Haukeland University Hospital, Bergen, Norway.ORCID 0000-0002-4216-7891
Jan-Erik GjertsenDepartment of Clinical Medicine, University of Bergen, Bergen; The Norwegian Arthroplasty Register, Department of Orthopaedic Surgery, Haukeland University Hospital, Bergen, Norway.ORCID 0000-0002-8490-268X
Ove FurnesDepartment of Clinical Medicine, University of Bergen, Bergen; The Norwegian Arthroplasty Register, Department of Orthopaedic Surgery, Haukeland University Hospital, Bergen, Norway.ORCID 0000-0001-8223-2515

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeTourniquet use in total knee arthroplasty (TKA) provides a bloodless surgical field, which may lead to a better cementation but reduced function and increased pain. We aimed to investigate the effect of a tourniquet during TKA on implant survival, implant loosening, infection, and mortality.

methodsData from 24,249 TKAs, collected by the Norwegian Arthroplasty Register between 2019 and 2023, was included. Among these, 14,926 were operated on with tourniquet and 9,323 without tourniquet. Cumulative revision rates (CRRs) were estimated using 1 minus Kaplan-Meier estimates for all revision causes and Cumulative Incidence Function (CIF) for specific revision causes at 3 years of follow-up. Cox regression analyses estimated hazard rate ratios (HRRs) for all revisions and Fine and Gray analyses estimated sub-hazard ratios (SHRs) for specific revision causes. Both were adjusted for age, sex, diagnosis, ASA score, fixation, implant type, and tranexamic acid use.

resultsAt 3 years of follow-up CRR was lower for the tourniquet group at 2.49% (95% confidence interval [CI] 2.21-2.81) vs 3.59% (CI 3.14-4.10) for the non-tourniquet group. We found an increased risk of revision in the non-tourniquet group (HRR 1.81, CI 1.46-2.46) after 3 months. CIF demonstrated a lower CRR for aseptic tibial loosening for the tourniquet group (0.08%, CI 0.04-0.15) compared with the non-tourniquet group (0.39%, CI 0.25-0.58). There was a higher risk of aseptic tibial loosening for non-tourniquet TKAs (SHR 6.06, CI 3.06-12.00), but no association with aseptic femoral loosening. There was no difference in infection or mortality.

conclusionTourniquet use during TKA was associated with reduced risk of tibial loosening after 3 years but without increased risk of infection, femoral loosening, or mortality.

Indexed as

Arthroplasty, Replacement, KneeKnee ProsthesisProsthesis FailureTourniquetsAgedAged, 80 and overFemaleHumansMaleMiddle AgedNorwayRegistriesReoperation

Identifiers

PMID40698895
PMCPMC12285508

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.