Evidence map›Paper›PMID 40698818›Full record

ArticleAntimicrobial agents and chemotherapy2025

Driving factors for beta-lactam resistance gene amplification during

Luyuan Nong, Xinwei Liu, Xinyu Wang, Wim de Leeuw, Martijs Jonker, Stanley Brul, Benno Ter Kuile

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Luyuan NongSwammerdam Institute of Life Sciences, University of Amsterdam, Amsterdam, the Netherlands.
Xinwei LiuSwammerdam Institute of Life Sciences, University of Amsterdam, Amsterdam, the Netherlands.
Xinyu WangSwammerdam Institute of Life Sciences, University of Amsterdam, Amsterdam, the Netherlands.
Wim de LeeuwSwammerdam Institute of Life Sciences, University of Amsterdam, Amsterdam, the Netherlands.
Martijs JonkerSwammerdam Institute of Life Sciences, University of Amsterdam, Amsterdam, the Netherlands.
Stanley BrulSwammerdam Institute of Life Sciences, University of Amsterdam, Amsterdam, the Netherlands.ORCID 0000-0001-5706-8768
Benno Ter KuileSwammerdam Institute of Life Sciences, University of Amsterdam, Amsterdam, the Netherlands.ORCID 0000-0002-8523-8135

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long-term exposure of

Indexed as

beta-Lactamasesbeta-Lactam Resistancebeta-LactamsEscherichia coliGene AmplificationAmoxicillinAnti-Bacterial AgentsBacterial ProteinsEscherichia coli ProteinsEvolution, MolecularMicrobial Sensitivity TestsTetracyclineAmoxicillinAmpC beta-lactamasesAnti-Bacterial AgentsBacterial Proteinsbeta-Lactamasesbeta-LactamsEscherichia coli ProteinsTetracyclineampCbeta-lactam antibioticsgene amplificationgene translocation

Identifiers

PMID40698818
PMCPMC12406687

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.