Evidence map›Paper›PMID 40698695›Full record

ReviewCurrent cancer drug targets2026

Migrasomes: A Novel Target for Cancer Treatment.

Neha Sharma, Anurag Chaudhary

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current cancer drug targets, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Neha SharmaDepartment of Pharmaceutical Technology, Meerut Institute of Engineering and Technology, NH-58, Baghpat Road Crossing, Bypass Road, Meerut-250005, India.
Anurag ChaudharyDepartment of Pharmaceutical Technology, Meerut Institute of Engineering and Technology, NH-58, Baghpat Road Crossing, Bypass Road, Meerut-250005, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Protrusion and adhesion occur at the foremost point of cells during cell migration, while contraction and detachment occur at the rear of the cells. The combined action of cytoskeletal dynamics, vesicular trafficking, and signaling networks initiates this multistep process. The development of a novel exosome-like organelle called migrasomes, which may play roles in intercellular signaling, and which originate from retraction fibers at the back of migrating cells. Migrasomes are a particular kind of extracellular vesicle that is placed by a special mechanism and left behind by migrating cells. The proteins called integrins, which connect cells to the extracellular matrix (ECM), regulate the mobilization of migrasome. The function of migrasomes is to preserve cellular homeostasis and communication between cells. By observing this literature, we attempted to ascertain the potential role that migrasomes will play in the future in illnesses involving migrating cells, like immune system problems, tumor metastasis, and other disorders.

Indexed as

Antineoplastic AgentsCell MovementExosomesNeoplasmsAnimalsCell AdhesionExtracellular MatrixHumansIntegrinsSignal TransductionAntineoplastic AgentsIntegrinsContractiondetachmentimmune systemsmigrasomesretraction fiberstumors

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.