Evidence map›Paper›PMID 40698689›Full record

ReviewCurrent drug discovery technologies2026

Edible Vaccines: A Paradigm Shift in Vaccine Delivery and Global Health Solutions.

Gulpreet Mehra, Anjana Sharma, Nitin Sharma

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current drug discovery technologies, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Gulpreet MehraDepartment of Pharmaceutics, Amity Institute of Pharmacy, Amity University, Noida, Uttar Pradesh, 201301, India.
Anjana SharmaLloyd Institute of Management and Technology, Plot No. 11, Knowledge Park-II, Greater Noida, 201306, India.ORCID 0000-0002-3745-8803
Nitin SharmaDepartment of Pharmaceutics, Amity Institute of Pharmacy, Amity University, Noida, Uttar Pradesh, 201301, India.ORCID 0000-0001-6682-748X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Edible vaccines represent a revolutionary approach to immunization, leveraging genetically modified plants to produce antigens that elicit immune responses when consumed. This novel strategy addresses several limitations of traditional vaccines, particularly in resource-limited settings, by eliminating the need for cold-chain logistics and skilled healthcare personnel for administration. Edible vaccines can enhance patient compliance, especially among children, by providing a noninvasive method of immunization. Recent advancements have demonstrated the potential of edible vaccines to prevent various infectious diseases. However, challenges remain, including the risk of immune tolerance, variability in antigen dosage, and regulatory hurdles. This review highlights the mechanisms of antigen expression in edible vaccine platforms, engineering strategies to enhance stability and efficacy, and recent clinical trials that underscore their potential impact on global health initiatives.

Indexed as

Vaccines, EdibleAnimalsGlobal HealthHumansImmune TolerancePlants, Genetically ModifiedVaccines, Edibleantigen expressionEdible vaccinesgenetically modified plantsimmune dosageimmune toleranceimmunization

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.