ArticleThoracic cancer2025
Segmentectomy Versus Lobectomy in Early Non-Small Cell Lung Cancer: A Population-Based Analysis in Northern Italy.
Article in Thoracic cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Segmentectomy Versus Lobectomy in Early Non-Small Cell Lung Cancer: A Population-Based Analysis in Northern Italy.Thoracic cancer · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough smoking cessation remains the most effective preventive measure against lung cancer, the implementation of low-dose computed tomography screening has facilitated early tumor detection, increasing the need for less invasive surgical approaches. This study evaluated the efficacy of segmentectomy vs. lobectomy for early-stage non-small cell lung cancer (NSCLC) in northern Italy. MATERIAL AND
methodsThe analysis included 200 patients with stage I NSCLC, selected from a cancer registry. Of these, 100 underwent lobectomy and 100 underwent segmentectomy. We calculated loco-regional and distant recurrences, overall survival, and disease-free survival (DFS).
resultsOver a median follow-up of 6.3 years, segmentectomy was associated with a lower recurrence rate (28%) compared to lobectomy (35%) and a lower incidence of distant metastases (39.6% vs. 60.4%). Multivariable analysis showed a greater risk of recurrence in patients undergoing lobectomy [OR 1.32; 95% CI: 0.71-2.45] and in females [OR 1.69; 95% CI: 0.89-3.18], while a decreased risk was observed among elderly patients over 70 years [OR 0.72; 95% CI: 0.39-1.32] and those with adenocarcinoma histology [OR 0.82; 95% CI: 0.41-1.64]. Five-year survival was higher in the segmentectomy group (67%; 95% CI: 57-76) compared to the lobectomy group (55%; 95% CI: 45-65); a similar result was observed for DFS: 59% (95% CI: 48-68) versus 47% (95% CI 37-57). The risk of death appeared lower in the segmentectomy group [HR 0.85; 95% CI: 0.59-1.22]. DISCUSSION: The outcomes appear to favor segmentectomy, as previously demonstrated in clinical trials. The observed effects are less pronounced, due to the absence of patient selection in this real-world setting.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.