Evidence map›Paper›PMID 40698517›Full record

ReviewJournal of primary care & community health

Harnessing Artificial Intelligence and Innovative Vaccines for Mpox Diagnosis and Control: A Comprehensive Narrative Review.

Excel Onajite Ernest-Okonofua, Zainab Abdullahi Zubairu, Malik Olatunde Oduoye, Maryam Tariq, Syed Muhammad, Zainab Siddiqua, Monica Vuyyuru, Benjamin Wafula, Riaz Akhtar, Abdulbasit Fasasi and 2 more

Abstract readReview
In one paragraph

Review in Journal of primary care & community health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Excel Onajite Ernest-OkonofuaUniversity of South Wales, UK.
Zainab Abdullahi ZubairuAhmadu Bello University, Zaria, Kaduna State, Nigeria.
Malik Olatunde OduoyeThe Medical Research Circle (MedReC), Goma, Democratic Republic of Congo.ORCID 0000-0001-9635-9891
Maryam TariqAziz Fatimah Medical and Dental College, Faisalabad, Pakistan.
Syed MuhammadFarooqia College of Pharmacy, Mysuru, Karnataka, India.
Zainab SiddiquaGandhi Medical College, Secunderabad, Telangana, India.
Monica VuyyuruGandhi Medical College, Secunderabad, Telangana, India.
Benjamin WafulaUzima University, Kisumu, Kenya.
Riaz AkhtarBacha Khan Medical College Mardan, Pakistan.
Abdulbasit FasasiUniversity of Ilorin, Nigeria.
Samuel Chinonso UbechuYale University, New Haven, CT, USA.
Bakare Sikiru OlayinkaFederal Medical Center, Bida, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe re-emergence of monkeypox (mpox) has triggered a global alert and galvanized efforts toward a scientific reappraisal of the disease.

aimThis study aims to provide a review of the use of Artificial Intelligence (AI) and novel vaccines in reducing the burden of mpox. METHODOLOGY: A narrative review was conducted according to Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines through electronic databases including PubMed, Google Scholar, ResearchGate, and Web of Science (WOS), using keywords such as Mpox, machine learning, deep learning, diagnosis and novel vaccines between the last 5 years (2019-2024). Included studies comprised clinical trials, cross-sectional studies, systematic reviews, meta-analyses, case reports, and case series written in the English language.

resultThe diagnosis of mpox has been greatly aided by the use of AI, including machine learning (ML), deep learning (DL), artificial neural network (ANN), convolutional neural network (CNN), and transfer learning (TL). AI can help with the development of novel diagnostic tests, increasing the accuracy and speed of mpox detection, which is critical for successful epidemic management. Reported model accuracies for mpox lesion classification and disease trend prediction ranged from 83 to 99.8%, underscoring the high potential of AI-based tools in this field. Vaccines developed against smallpox, such as ACAM2000, LC16m8, and MVA-BN (JYNNEOS), have shown partial efficacy in preventing mpox transmission, providing cross-protection against mpox due to the genetic similarity between the 2 viruses.

conclusionAI has proven to be significant in mpox detection, treatment, and prevention. Future directions should be focused on healthcare professionals to establish the validity and reliability of the models, a measure of the algorithm's robustness, and the continuous auditing of AI systems.

Indexed as

Artificial IntelligenceMpox, MonkeypoxDeep LearningHumansMachine LearningNeural Networks, Computerdeep learningdetectiondiagnosisidentificationmachine learningmpoxnovel vaccines

Identifiers

PMID40698517
PMCPMC12290340

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.