ReviewMicrobiologyOpen2025
Analyzing the Challenges and Opportunities Associated With Harnessing New Antibiotics From the Fungal Microbiome.
Review in MicrobiologyOpen, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Snapshot reflection of the seasonal resilience and diversity of fungal phylotypes in the tropical Ikogosi spring.Environmental science and pollution research international · 2026Article
- Amazonian Fungal Diversity and the Potential of Basidiomycetes as Sources of Novel Antimicrobials.Biology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
The rapid rise in antibiotic resistance is a critical global health issue, and few new classes of antibiotics have been discovered since 1990 compared to the antibiotic's golden era between 1950 and 1970. However, developing new antimicrobial compounds faces many challenges, improvements in cultivation methods, genetic engineering, and advanced technologies are opening new paths for discovering and producing effective antibiotics. This study focuses on the fungal microbiome as a promising source of new antibiotics. We explored historical developments and advanced genetic techniques to reveal the potential of fungi in antibiotic production. Although isolating and scaling up fungal antibiotic production presents challenges, innovative approaches like in situ separation during fermentation can effectively address these issues. Our research highlights the importance of understanding fungal communication and metabolite sharing to enhance antibiotic yields and the connection of cutting-edge technologies in accelerating the discovery and optimization of antibiotic-producing fungi. By focusing on these technical aspects and fostering teamwork across various fields, this study aims to overcome current obstacles, and advance the development of antibiotic production technologies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.