Evidence map›Paper›PMID 40698376›Full record

ArticleInternational journal of cardiology. Congenital heart disease2025

Late diagnosis of severe aortic coarctation in a 65-year-old endurance athlete: Insights into exercise physiology and collateral compensation.

Arundhati Sharma, Anubhuti Sharma, Kalyan Chaliki, Marco Antonio Fernandes, Francois Marcotte, Satyajit Reddy

Abstract readCase Reports
In one paragraph

Article in International journal of cardiology. Congenital heart disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Arundhati SharmaMayo Clinic, 13400 E, Shea Blvd, Scottsdale, AZ, 85259, USA.
Anubhuti SharmaMayo Clinic, 13400 E, Shea Blvd, Scottsdale, AZ, 85259, USA.
Kalyan ChalikiThe University of Arizona College of Medicine - Phoenix, 475 N 5th St, Phoenix, AZ, 85004, USA.
Marco Antonio FernandesLoyola Marymount University, Loyola Marymount University Dr, Los Angeles, CA, 90045, USA.
Francois MarcotteMayo Clinic, 13400 E, Shea Blvd, Scottsdale, AZ, 85259, USA.
Satyajit ReddyMayo Clinic, 13400 E, Shea Blvd, Scottsdale, AZ, 85259, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Coarctation of the aorta (CoA) is a relatively rare congenital narrowing of the distal aortic arch to proximal descending thoracic aorta, usually diagnosed in infancy or early childhood with upper extremity hypertension as a typical finding. Late detection in asymptomatic, physically active older adults is rare and can be clinically significant. Case presentation: We present the case of a 65-year-old lifelong endurance athlete found to have transient severe left ventricular (LV) systolic dysfunction after completing a marathon. Stress testing revealed a hypertensive response, prompting cardiac MRI, which detected a new severe juxta-ductal CoA with collateralization. The patient underwent successful endovascular stenting with improved blood pressure response and stabilization of LV function. Conclusion: This case underscores the importance of thorough cardiovascular assessment in older athletes and highlights the impact of lifelong exercise in compensating for congenital defects like CoA.

Indexed as

Coarctation of aortaExertional hypertensionLeft ventricular dysfunction

Identifiers

PMID40698376
PMCPMC12281131

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.