Evidence map›Paper›PMID 40698171›Full record

ArticleAlzheimer's & dementia (New York, N. Y.)

Comprehensive intervention combining group and personalized language therapy in primary progressive aphasia: Quantitative and qualitative findings.

Tijana Simic, Laura Laird, Rudra Patel, Monica Lavoie, Maria Martinez, Paula Gosse, Alexandra Santos, David Tang-Wai, Regina Jokel, Carmela Tartaglia and 1 more

Abstract read
In one paragraph

Article in Alzheimer's & dementia (New York, N. Y.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Tijana SimicDepartment of Speech-Language Pathology University of Toronto Toronto Ontario Canada.ORCID https://orcid.org/0000-0001-6638-6514
Laura LairdDepartment of Speech-Language Pathology University of Toronto Toronto Ontario Canada.
Rudra PatelDepartment of Speech-Language Pathology University of Toronto Toronto Ontario Canada.
Monica LavoieFondation de la famille Lemaire Université Laval, Québec Québec City Canada.
Maria MartinezUniversity Health Network Memory Clinic Toronto Western Hospital Toronto Ontario Canada.
Paula GosseUniversity Health Network Memory Clinic Toronto Western Hospital Toronto Ontario Canada.
Alexandra SantosUniversity Health Network Memory Clinic Toronto Western Hospital Toronto Ontario Canada.
David Tang-WaiUniversity Health Network Memory Clinic Toronto Western Hospital Toronto Ontario Canada.
Regina JokelDepartment of Speech-Language Pathology University of Toronto Toronto Ontario Canada.
Carmela TartagliaUniversity Health Network Memory Clinic Toronto Western Hospital Toronto Ontario Canada.
Elizabeth RochonDepartment of Speech-Language Pathology University of Toronto Toronto Ontario Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIncreasingly, studies are demonstrating language and communication improvement after behavioral interventions for primary progressive aphasia (PPA), and the caregiver perspective has been highlighted as critically important to determining treatment success in this population. This is an exploratory study investigating a comprehensive, person-centered intervention promoting everyday communication, functional independence, and quality of life for people with PPA (PwPPA) and their caregivers.

methodsFour intervention programs were run separately in 6 to 8 week blocks with a total of 14 dyads (PwPPA and caregiver) enrolled. Group sessions lasted 2 hours and included communication strategy training, PPA education from multidisciplinary experts, speech therapy for PwPPA, and a support group for caregivers (blocks 1 and 2). Personalized language exercises were assigned for home practice, using apps or paper-and-pencil tasks. Quantitative and qualitative outcomes were measured before and after each treatment block and included: the Revised Western Aphasia Battery (WAB-R) Aphasia Quotient (AQ) and subtest scores, content information units (CIUs) on the WAB-R picture description task, and qualitative content analysis of semi-structured interviews, gathered from both PwPPA and caregivers.

resultsNo statistically significant changes were noted in mean WAB-AQ score pre- to post-intervention. Mean CIUs produced on the WAB-R picture description task pre- to post-intervention increased and approached significance ( DISCUSSION: Further investigation into the most appropriate assessment tools and intervention approaches for PPA is warranted and has the potential to make a significant positive impact on PwPPA and their families. Highlights: We combined quantitative and qualitative measures of efficacy in treating primary progressive aphasia.Language skills were maintained and communication improvement approached significance.Participants noted the benefits of peer support, education, and communication practice.

Indexed as

caregiver supportcommunicationgroup therapyinterventionlanguageprimary progressive aphasia

Identifiers

PMID40698171
PMCPMC12281019

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.