Evidence map›Paper›PMID 40698118›Full record

ArticleInternational journal of chronic obstructive pulmonary disease2025

Upregulation of ARHGAP18 by miR-613 Inhibits Cigarette Smoke Extract-Induced Apoptosis and Epithelial-Mesenchymal Transition in Bronchial Epithelial Cells.

Haifan Fu, Kai Liu, Yamei Zheng, Jie Zhao, Tian Xie, Yipeng Ding

Abstract read
In one paragraph

Article in International journal of chronic obstructive pulmonary disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. miR-766-5p Attenuates Cigarette Smoke-Induced COPD by Targeting MAPK1.Journal of biochemical and molecular toxicology · 2026
    Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Haifan Fu *Yangjiang Health Center of Qionghai County, Qionghai, Hainan Province, People's Republic of China.
Kai Liu *Department of Pulmonary and Critical Care Medicine, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, People's Republic of China.
Yamei ZhengDepartment of Pulmonary and Critical Care Medicine, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, People's Republic of China.
Jie ZhaoDepartment of Pulmonary and Critical Care Medicine, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, People's Republic of China.
Tian XieDepartment of Pulmonary and Critical Care Medicine, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, People's Republic of China.
Yipeng DingDepartment of General Practice, Hainan Affiliated Hospital of Hainan Medical University, Hainan General Hospital, Haikou, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Chronic Obstructive Pulmonary Disease (COPD) is a major chronic respiratory disease affecting human health worldwide. However, there is still a lack of effective drugs for treating COPD. This study is intended to explore the function and molecular mechanism of Methods: We initially identified the marker gene closely related to epithelial dysfunction in COPD by integrating bioinformatic analyses. Results: Our study identified Conclusion: These findings highlight miR-613/

Indexed as

ApoptosisBronchiCigarette SmokingEpithelial CellsEpithelial-Mesenchymal TransitionGTPase-Activating ProteinsMicroRNAsPulmonary Disease, Chronic ObstructiveSmokeCadherinsCell LineCell MovementHumansSignal TransductionTumor Necrosis Factor-alphaUp-RegulationCadherinsGTPase-Activating ProteinsMicroRNAsSmokeTumor Necrosis Factor-alphaapoptosisARHGAP18chronic obstructive pulmonary diseaseepithelial-mesenchymal transitionmiR-613

Identifiers

PMID40698118
PMCPMC12282545

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.