ArticleFrontiers in psychiatry2025
Burden of autism spectrum disorder in Japan from 1992 to 2021 and its prediction until 2050: results from the GBD study.
Article in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed.
- Sports and physical activity interventions in autism spectrum disorder: a systematic literature review and meta-analysis.Frontiers in sports and active living · 2026Article
- Altered cortical activation and functional connectivity during fixed phrase verbal fluency in children with autism spectrum disorder.Frontiers in psychiatry · 2026Article
- Trends in burden of falls among children aged 0-14 years in China from 1990-2021 and prediction to 2030.Frontiers in public health · 2025Article
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6 authors.
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Abstract
Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by persistent deficits in social communication and interaction, alongside restricted, repetitive patterns of behavior. This study aimed to analyze the temporal trends and project the future burden of ASD in Japan. Using Global Burden of Disease (GBD) 2021 data, we analyzed prevalence, disability-adjusted life years (DALYs), and age-standardized rates (ASR) (1992-2021) through age-period-cohort modeling, joinpoint regression, and autoregressive integrated moving average (ARIMA) forecasting. Age-standardized prevalence rate (ASPR) increased significantly (Average Annual Percentage Change [AAPC]=0.2744; 95%CI:0.2606-0.2882), with males disproportionately affected (male-to-female ratio 4:1). By 2050, crude prevalence is projected to decline 14.2%, while ASPR will rise 18.0%. Japan's ASD burden exceeds global averages, necessitating targeted interventions across the lifespan. These findings highlight the increasing burden of ASD in Japan and underscore the urgent need for enhanced healthcare planning and resource allocation.
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