ArticleClinical kidney journal2025
The diagnostic accuracy of ultrasound and genomic tests for the diagnosis of autosomal-dominant polycystic kidney disease: a systematic mapping review.
Article in Clinical kidney journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
Background: Genomic and ultrasound tests can provide diagnostic and prognostic information on autosomal-dominant polycystic kidney disease (ADPKD), and can screen first-degree relatives in whom early diagnosis can be advantageous. We conducted a systematic mapping review on test accuracy and characteristics over time. Methods: Medline, Embase, and Cochrane were searched (August 2023) for studies in first Results: From 1029 non-duplicate titles retrieved, 51 genomic and 7 ultrasound studies were included. There were no genomic studies in first-degree relatives. Among studies in patients with clinical diagnoses, genomic sequencing methodologies were highly heterogeneous [next generation (short read ( Conclusions: Despite technological advances, sensitivity of genomic tests appeared static between 2000 and 2023. Possible explanations include clinical diagnostic criteria (and hence populations recruited) widening from
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