Evidence map›Paper›PMID 40697890›Full record

ArticleArthroplasty today2025

Association Between Total Joint Arthroplasty and Surgical Complications in Patients With Valvular Heart Replacement: An Observational Study.

Amir Human Hoveidaei, Sina Esmaeili, Homina Saffar, Aref Ghanaatpisheh, Fatemeh Zarepour, Amirhossein Shirinezhad, Henry Tout Shu, Janet D Conway

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Article in Arthroplasty today, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Amir Human HoveidaeiInternational Center for Limb Lengthening, Rubin Institute for Advanced Orthopedics, Sinai Hospital of Baltimore, Baltimore, MD, USA.
Sina EsmaeiliSina University Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Homina SaffarStudent Research Committee, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Aref GhanaatpishehStudent Research Committee, Jahrom University of Medical Sciences, Jahrom, Iran.
Fatemeh ZarepourSchool of medicine, Kashan University of Medical Sciences, Kashan, Iran.
Amirhossein ShirinezhadSchool of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Henry Tout ShuDepartment of Orthopaedic Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Janet D ConwayInternational Center for Limb Lengthening, Rubin Institute for Advanced Orthopedics, Sinai Hospital of Baltimore, Baltimore, MD, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Valvular heart replacement (VHR) is associated with increased cardiac complications and mortality risk in patients undergoing noncardiac surgery. There are limited data on total joint arthroplasty outcomes in patients with a prior history of VHR. Methods: In this retrospective cohort study, we identified patients who underwent elective total hip arthroplasty (THA) and total knee arthroplasty (TKA) between 2010 and 2022 using the PearlDiver national database. Patients with a history of VHR were matched with a control group using propensity score matching. Statistical analyses were conducted using R statistical software. Results: We identified 874 patients with THA and 1162 patients with TKA. No significant difference in surgical or medical complications was observed in THA patients with a history of VHR compared to the matched control group, regardless of the time interval between procedures. In contrast, for TKA patients, VHR was associated with a higher incidence of periprosthetic joint infection (odds ratio [OR] = 1.54; 95% confidence interval [CI]: 1.02-2.33; Conclusions: VHR was not associated with an increased risk of complications following THA. However, about TKA patients, a history of VHR was linked to a higher risk of periprosthetic joint infection, and an increased incidence of cerebrovascular accident in those who had VHR 3 to 6 months prior. Future studies are needed to develop strategies for reducing complications. Level of Evidence: III (Retrospective cohort).

Indexed as

OutcomeSurgical complicationsTotal joint arthroplastyValvular heart replacement

Identifiers

PMID40697890
PMCPMC12281530

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.