Evidence map›Paper›PMID 40697797›Full record

ArticleAnnals of clinical epidemiology2025

Risk factors for nephropathy in individuals with new-onset type 2 diabetes undergoing treatment for hypertension: A retrospective analysis using the Diagnosis Procedure Combination database.

Tomoko Ishigaki Suzuki, Mari Saito Oba, Kohei Uemura

Abstract read
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Article in Annals of clinical epidemiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Tomoko Ishigaki SuzukiDepartment of Biostatistics and Information, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Mari Saito ObaClinical Research & Education Promotion Division, National Center of Neurology and Psychiatry, Tokyo, Japan.
Kohei UemuraInterfaculty Initiative in Information Studies, The University of Tokyo, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiabetic nephropathy is a common complication of diabetes. We investigated the risk factors for diabetic nephropathy in individuals newly diagnosed with type 2 diabetes.

methodsData from the Japanese Diagnosis Procedure Combination in-patient database (April 2008 to December 2018) were analyzed. The endpoint was subsequent diabetic nephropathy diagnosis or as the time when estimated glomerular filtration rate become <60 ml/min/1.73 m

resultsOf 2,664 eligible individuals (1,775 men, 889 women), 325 men and 175 women developed diabetic nephropathy during follow-up. Cumulative incidence within 5 years was 29.0% in men and 32.5% in women. Age and estimated glomerular filtration rate in both sexes, and total cholesterol in men were significant.

conclusionsAge, estimated glomerular filtration rate, and lipid pose potential risks for diabetic nephropathy onset within 5 years of diabetes diagnosis in individuals with hypertension. Collectively, our findings highlight the importance of early monitoring and intervention in this high-risk.

Indexed as

hypertension treatmentnew type 2 diabetesOnset of diabetic nephropathyrisk factor

Identifiers

PMID40697797
PMCPMC12279404

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.