Evidence map›Paper›PMID 40697756›Full record

ReviewCurrent research in food science2025

Probiotics as a therapeutic strategy for metabolic dysfunction-associated steatotic liver disease: A systematic review and meta-analysis.

Jing Lu, Xiaoxiao Dong, Ziqi Gao, Huizhen Yan, Dilireba Shataer, Liang Wang, Yanan Qin, Minwei Zhang, Jiayi Wang, Jie Cui and 1 more

Abstract readReview
In one paragraph

Review in Current research in food science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Journal of microbiology and biotechnology · 2026
    Article
  3. Sarcopenia and MASLD: novel insights and the future.Nature reviews. Endocrinology · 2026
    Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jing LuCollege of Smart Agriculture (Research Institute), Xinjiang University, Urumqi, 830046, China.
Xiaoxiao DongCollege of Smart Agriculture (Research Institute), Xinjiang University, Urumqi, 830046, China.
Ziqi GaoCollege of Smart Agriculture (Research Institute), Xinjiang University, Urumqi, 830046, China.
Huizhen YanCollege of Smart Agriculture (Research Institute), Xinjiang University, Urumqi, 830046, China.
Dilireba ShataerCollege of Smart Agriculture (Research Institute), Xinjiang University, Urumqi, 830046, China.
Liang WangCollege of Smart Agriculture (Research Institute), Xinjiang University, Urumqi, 830046, China.
Yanan QinCollege of Smart Agriculture (Research Institute), Xinjiang University, Urumqi, 830046, China.
Minwei ZhangCollege of Smart Agriculture (Research Institute), Xinjiang University, Urumqi, 830046, China.
Jiayi WangCollege of Smart Agriculture (Research Institute), Xinjiang University, Urumqi, 830046, China.
Jie CuiCollege of Food Science and Light Industry, Nanjing Tech University, Nanjing, 211816, China.
Shengyang ZhouCollege of Smart Agriculture (Research Institute), Xinjiang University, Urumqi, 830046, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metabolic dysfunction-associated steatotic liver disease (MASLD) is recognized as one of the most common chronic liver conditions globally, presenting a significant public health. Probiotics, as modulators of intestinal microbiota, have emerged attention as a potential therapeutic strategy for managing MASLD. This systematic review and meta-analysis encompassed 12 randomized controlled trials including 657 participants to quantify the effects of probiotic supplementation on liver function indicators, lipid metabolism, and inflammatory markers in MASLD patients. Compared with placebo, probiotics significantly reduced liver-related measures, including alanine aminotransferase (ALT), aspartate aminotransferase (AST), and γ-glutamyl transaminase (GGT) levels (MD

Indexed as

Lipid profileMeta-analysisMetabolic dysfunction-associated steatotic liver diseaseProbioticsSystematic review

Identifiers

PMID40697756
PMCPMC12281447

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.