Evidence map›Paper›PMID 40697721›Full record

ArticleJournal of contemporary brachytherapy2025

Post-surgical brachytherapy in the treatment of keloids: A single-center study.

Irene Gonzalez-Alaña, Patricia Martin-Playa, Leire Aparicio-Elizalde, Unay Yilmaz-Bescos, Francisco Casquero-Ocio, Itziar Valverde-Pascual, Silvia Perez-Fernandez, Jaime Carames-Estefania, Iñigo San Miguel-Arregui

Abstract read
In one paragraph

Article in Journal of contemporary brachytherapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Irene Gonzalez-AlañaCruces University Hospital, Barakaldo, Spain.
Patricia Martin-PlayaCruces University Hospital, Barakaldo, Spain.
Leire Aparicio-ElizaldeCruces University Hospital, Barakaldo, Spain.
Unay Yilmaz-BescosCruces University Hospital, Barakaldo, Spain.
Francisco Casquero-OcioCruces University Hospital, Barakaldo, Spain.
Itziar Valverde-PascualCruces University Hospital, Barakaldo, Spain.
Silvia Perez-FernandezCruces University Hospital, Barakaldo, Spain.
Jaime Carames-EstefaniaCruces University Hospital, Barakaldo, Spain.
Iñigo San Miguel-ArreguiSalamanca University Care Complex, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: A keloid is a benign fibro-dermal tumor that produces an excess deposit of extra-cellular matrix. It usually occurs after a skin lesion, and it spreads beyond the wound. It is characterized by high recurrence rate after excision and lack of tendency of spontaneous involution. Multiple treatments have been described, with recurrence rates of up to 100%. One of the treatments considered most effective is combined therapy, i.e., surgery and subsequent radiotherapy using interstitial irradiation with iridium-192 (brachytherapy), with a clear reduction in recurrence rate. Material and methods: In our center, the technique was introduced in 2012, and the current retrospective observational study was conducted among 27 patients treated till December 2020. Results: The recurrence rate in the study was 25%, of which 83% recurred partially. Conclusions: The most frequent complications observed were dehiscence and infection of the surgical wound, therefore this therapeutic approach can be considered both safe and effective.

Indexed as

brachytherapycombined treatmentexcisionkeloidsurgery

Identifiers

PMID40697721
PMCPMC12277957

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.