Evidence map›Paper›PMID 40697701›Full record

ArticleFood science & nutrition2025

Unlocking Resveratrol's Potential: Targeting Ferroptosis in Atherosclerosis Through MAPK1.

Yao Zhang, Jun Cheng, Wu Jian

Abstract read
In one paragraph

Article in Food science & nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yao ZhangDepartment of Inspection Changde Hospital, Xiangya School of Medicine, Central South University (The first people's hospital of Changde city) Changde Hunan China.ORCID https://orcid.org/0000-0002-7481-4053
Jun ChengDepartment of Inspection Changde Hospital, Xiangya School of Medicine, Central South University (The first people's hospital of Changde city) Changde Hunan China.
Wu JianDepartment of Inspection Changde Hospital, Xiangya School of Medicine, Central South University (The first people's hospital of Changde city) Changde Hunan China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atherosclerosis (AS) is a chronic inflammatory metabolic disorder and a leading cause of cardiovascular diseases. Resveratrol (RSV), a natural polyphenolic phytoestrogen, exhibits anti-atherosclerotic effects by modulating oxidative stress and ferroptosis, yet its key therapeutic targets remain unclear. Using network pharmacology, bioinformatics, machine learning, and molecular docking, we identified core targets and mechanisms of RSV in ferroptosis and anti-atherosclerosis. Experimental validation was performed using ApoE

Indexed as

atherosclerosisferroptosismachine learningMAPK1molecular dockingresveratrol

Identifiers

PMID40697701
PMCPMC12280227

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.