ArticleWorld journal of diabetes2025
Altered hippocampal subfield volumes are associated with memory and executive function in patients with type 2 diabetes mellitus.
Article in World journal of diabetes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Progressive modeling of multiscale hippocampal subfield structural representation improves the prediction performance of mild cognitive impairment in type 2 diabetes.European archives of psychiatry and clinical neuroscience · 2026Article
- Nicotinamide Riboside (NR) Supplementation Exerts Neuroprotective Effects in db/db Mouse Model of Type 2 Diabetes.Journal of molecular neuroscience : MN · 2026Article
- Brain over muscle: central mechanisms predominate in gait impairment among older adults with type 2 diabetes mellitus.Frontiers in aging neuroscience · 2026Article
- Dual-task timed up and go performance and sleep quality in relation to fall history in older adults with type 2 diabetes: a cross-sectional study.Frontiers in public health · 2026Observational
- Association of metabolic syndrome severity with cognitive decline among Chinese older adults: evidence from two prospective cohort studies.Frontiers in neuroscience · 2026Article
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Authors and funding
8 authors.
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Abstract
backgroundIncreasing evidence has shown that hippocampal damage serves as a marker of early cognitive decline in patients with type 2 diabetes mellitus (T2DM); however, the association between hippocampal subregion volume changes and cognitive decline in different dimensions remains unclear.
aimTo investigate changes in hippocampal subregion volumes in patients with T2DM and their relationship with cognitive function impairment.
methodsSixty patients with T2DM and 32 healthy controls were recruited. All participants underwent a 3.0 T magnetic resonance scan and a series of clinical assessments. Hippocampal subfield volumes were determined using FreeSurfer 7.4.1. A two-sample
resultsCompared with controls, the volume of right hippocampus-amygdala transition area (
conclusionDeclines in cognitive performance, especially memory and executive function, are linked to changes in the volumes of the right hippocampus-amygdala transition area and right molecular layer in patients with T2DM.
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