ArticleWorld journal of diabetes2025
Association of dietary index for gut microbiota and all-cause and cardiovascular mortality in patients with diabetes or prediabetes.
Article in World journal of diabetes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- The association between adapted dietary index for gut microbiota and carotid intima-media thickness among overweight or obese children and adolescents.Acta diabetologica · 2026Article
- Correlation Between Dietary Index for Gut Microbiota With All-Cause and Cardiovascular Mortality in Cardiovascular-Kidney-Metabolic Syndrome Patients.Food science & nutrition · 2026Article
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Authors and funding
5 authors.
Funding
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Abstract
backgroundThe dietary index for gut microbiota (DI-GM) demonstrates associations with diabetes prevalence and related mortality outcomes, serving as a nutritional assessment tool for microbial community evaluation.
aimTo investigate connections between DI-GM values and survival endpoints in populations with impaired glucose metabolism, incorporating both total mortality and cardiovascular-related fatal events.
methodsCox proportional hazards modeling through survival analysis evaluated the relationship between DI-GM quartile classifications and fatal event probabilities. Restricted cubic spline modeling evaluated non-linear associations between continuous DI-GM values and mortality endpoints. Stratified analyses and robustness checks ensured the validity of the results.
resultsHigher DI-GM values showed a statistically significant negative correlation with total mortality risk [hazard ratio (HR) = 0.96, 95%CI: 0.93-1.00] and cardiovascular-related fatal outcomes (HR = 0.93, 95%CI: 0.87-0.99). When comparing quartiles, analysis indicated that participants in the upper quartile (Q4) had 17% decreased likelihood of all-cause death (HR = 0.83, 95%CI: 0.69-0.99) and 25% lower probability of cardiovascular mortality (HR = 0.75, 95%CI: 0.54-1.00) relative to those in the lowest quartile (Q1).
conclusionThese findings position DI-GM as a protective determinant against mortality in glucose metabolism disorders. Dietary pattern optimization targeting DI-GM enhancement could constitute a strategic intervention in diabetes care protocols.
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